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Yearly Archives: 2010

Donations Ban on iPhone Apps Irritates Nonprofits

The nonprofit world is stewing over the ban Apple has put on making donations on the iPhone via charity apps. No one, including Apple, has data on how many nonprofits have created apps for the iPhone. Organizations like the Monterey

Posted in Around the Globe

What Is an Orphan Drug?

Pharmaceutical (drug) and biotech companies are constantly researching and developing new medications to treat medical conditions, and new drugs come on the market frequently. People who have rare diseases or disorders, however, have not had as much research attention in

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TYPES OF PEMPHIGUS

Pemphigus is a term used to describe blistering of the skin caused by binding of antibodies to the surface of the cells of the outer layer of the skin, the epidermis. In pemphigus vulgaris, the most common form of pemphigus,

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Consensus statement on definitions of disease, end points, and therapeutic response for pemphigus

Our scientific knowledge of pemphigus has dramatically progressed in recent years. However, despite the availability of various therapeutic options for the treatment of inflammatory diseases, only a few multicenter controlled trials have helped to define effective therapies in pemphigus. A

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Treatment of Pemphigus Vulgaris with Rituximab and Intravenous Immune Globulin

The risk of death in patients with pemphigusvulgaris has been substantially reduced by treat- ment with systemic corticosteroids.5 Current therapy consists of high doses of corticosteroids plus immunosuppressive agents.6 This combination frequently causes long-term immunosuppression, the consequences of which are

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Research Study in Pemphigus Vulgaris

Currently, available technologies are limited in their power to characterize autoreactive T cells, which are necessary for the generation of autoantibodies in PV and the development of disease. The research team of the Department of Dermatology at the Weill Medical

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How to Fight Stress and Ward Off Illness

“This new science is forcing the medical community to take more seriously the popular notions of the mind-body connection,” says Esther M. Sternberg, M.D., director of the Integrative Neural Immune Program at the National Institute of Mental Health. In response

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Drug Suits Raise Questions for Doctors, and Juries

The Unseen Problem With Drugs Judith Graves developed a rare medical condition called jawbone death after taking Fosamax, a drug used by millions of American women with thinning bones. The F.D.A. said the optimal period for using drugs like Fosamax

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Managing the Immunodulators

Dosage and indication “creep” with the new biologics to treat inflammatory diseases have payers enforcing strict utilization policies. Physicians counter that payers can’t dictate treatment. With even more biologics on the horizon, and drug spend spiralling upward, both sides need

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Bullous Pemphigoid: A Prototypical Antibody-Mediated Organ-Specific Autoimmune Disease

Bullous pemphigoid (BP) is a prototypical organ-specific autoimmune disease. Autoantibodies unfold their blister-inducing potential by triggering an Fcγ-dependent inflammatory reaction. The study by Iwata et al.  in this issue provides the first direct evidence that IgG autoantibodies from BP patients

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