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2012 | International Pemphigus Pemphigoid Foundation | Page 3
Yearly Archives: 2012

Autoimmune Diseases Facts

An autoimmune disease develops when the body’s immune system fails to recognize normal body tissues and attacks and destroys them as if they were foreign, rather than attacking an outside organism. The cause is not fully understood, but in some

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Pemphigus in Cats

Q. What is pemphigus? What is the best treatment? A. Pemphigus is a general term that describes four different disease entities, which we refer to as the Pemphigus Complex, primarily limited to the skin. All are considered to be immune mediated diseases.

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Has our war on microbes left our immune systems prone to dysfunction?

  An Epidemic of Absence: A New Way of Understanding Allergies and Autoimmune Diseases could be co-marketed with the Thomas Rockwell’s children’s classic How to Eat Fried Worms. It begins with the author, Moises Velasquez-Manoff, recounting his border-crossing to Tijuana to infect

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Hope For New Autoimmune Disease Treatment Using Rare Immune Cells

A new study in mice where researchers replicated a rare type of immune cell in the lab and then infused it back into the body, is raising hope for a new treatment for severe autoimmune diseases such as multiple sclerosis

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Results of surgical resection for patients with thymoma

OBJECTIVES: Thymomas are relatively rare tumors. In this study, we investigated the clinical features of patients who underwent surgical resection for thymoma. PATIENTS AND METHODS: This study clinicopathologically evaluated 54 consecutive patients who underwent a surgical resection of thymoma in

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Rituximab in pemphigus

Pemphigus is a chronic, muco-cutaneous autoimmune blistering disorder; two main variants being pemphigus vulgaris (PV) and pemphigus foliaceus (PF). PV is the most common subtype, varying between 75 to 92% of total pemphigus patients. Although no community based studies are undertaken

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Reflectance Confocal Microscopy As A New Tool

Background:  Desquamative gingivitis refers to a clinical manifestation associated with several mucocutaneous disorders. The most common are mucous membrane pemphigoid, pemphigus vulgaris and lichen planus. Their specific diagnosis is better established by histopathological and immunofluorescence evaluation. Objective:  To examine cases

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Randomized double blind trial of prednisolone and azathioprine

Background  The classic treatment for pemphigus vulgaris is prednisolone. Immunosuppressive drugs can be used in association. Objective  To compare the efficacy of Azathioprine in reducing the Disease Activity Index (DAI). Patients and methods  A double blind randomized controlled study was conducted on 56

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Ultrastructure of acantholysis in pemphigus foliaceus re-examined from the current perspective

Background  Pemphigus foliaceus (PF) is a chronic cutaneous autoimmune blistering disease that is characterized by superficial blistering of the skin, and according to the current perspective is caused by autoantibodies directed against desmoglein (Dsg) 1. Objectives  To examine early acantholysis

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Therapeutic targets for pemphigus vulgaris discovered

MedWire News: Researchers have identified the primary target of the autoantibodies found in the serum of patients with the blistering skin disorder pemphigus vulgaris (PV). PV patients develop antibodies against the proteins desmoglein (DSG)1 and 3, which help epidermal cells

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