Pemphigus can be a tough disease to live with but many patients now in remission have found inspiration, this is Sally’s story: I have been in remission now for over 1 year (YES!!!). That is complete remission with no symptoms…
Blog Archives
Paraneoplastic pemphigus associated with dendritic cell neoplasm and Castleman’s disease: report of a new case and review of the literature
We report on a patient with longstanding multicentric Castleman’s disease, hyaline-vascular type, who developed a follicular dendritic cell sarcoma, and finally presented a fatal paraneoplastic pemphigus. We review all four cases of such a triple association described in the…
Posted in Around the Globe
Prison Dermatology
Experience in the Texas Department of Criminal Justice Dermatology Clinic In this article, the authors review the skin conditions seen in a dermatology referral clinic for inmates in the Texas Department of Criminal Justice system at the University of Texas…
Tagged with: correctional health care, dermatology, inmates, skin conditions
Posted in Around the Globe
Posted in Around the Globe
A Case of Pyodermatitis-Pyostomatitis Vegetans.
Pyodermatitis-pyostomatitis vegetans (PD-PSV) is a rare disorder characterized by mucocutaneous involvement and associated with inflammatory bowel disease. A 42-year-old woman with ulcerative colitis who manifested verrucous and pyogenic lesions on her scalp, neck, axillae, inguinal areas, umbilicus, trunk and oral…
Tagged with: inflammatory bowel disease, lesions, PD-PSV
Posted in Around the Globe, News and Information
Posted in Around the Globe, News and Information
Oral aphthosis: management gaps and recent advances.
Introduction: Though oral aphthosis is common, it has a significant impact on the quality of life in the patients. It is the most common oral ulcerative condition encountered in clinical practice. This study describes the characteristics and patterns of oral…
Tagged with: oral aphthosis, pemphigus vulgaris, steroids
Posted in Around the Globe, News and Information
Posted in Around the Globe, News and Information
Oral pemphigus vegetans: A case report.
Pemphigus is a rare vesiculobullous autoimmune disease that exhibits blistering of the skin and oral cavity. It is caused by autoantibodies directed against antigens on the surface of keratinocytes. All forms of pemphigus are associated with the presence of circulating…
Tagged with: immunofluorescence, mucosal plaques, pemphigus vegetans, pemphigus vulgaris
Posted in Around the Globe, News and Information
Posted in Around the Globe, News and Information
Immunohistochemistry for immunoglobulin g4 on paraffin sections for the diagnosis of pemphigus.
Context.-Pemphigus is a group of autoimmune vesiculobullous diseases characterized by immunoglobulin G (IgG) antibodies directed against desmosomal adhesion proteins, with IgG4 being the predominant subclass in active diseases. Direct immunofluorescence for IgG performed on fresh-frozen tissue plays a crucial role…
Tagged with: immunofluorescence, immunoglobulin G, pemphigus, pemphigus foliaceus, vesiculobullous disease
Posted in Around the Globe, News and Information
Posted in Around the Globe, News and Information
Antidesmoglein antibodies in a patient with Hailey-Hailey disease
Abstract BACKGROUND: Hailey-Hailey disease (HHD) is a rare hereditary disease in which the genetic defect is characterized by mutation in the ATP2C1 gene coding for a transmembrane calcium pump. It is generally considered a non-immunologic acantholytic dermatosis in which direct…
Tagged with: acantholysis, antidesmoglein antibodies, Hailey-Hailey disease, transmembrane calcium pump
Posted in Around the Globe, News and Information
Posted in Around the Globe, News and Information
Acantholytic rosacea of the forehead and scalp in a patient with Hailey-Hailey disease
BACKGROUND: Rosacea is a common dermatosis that can involve the bald area of the scalp. We report the case of a man presenting clinical symptoms of rosacea of the forehead and the scalp, but with a histological picture of familial…
Tagged with: Acantholytic rosacea, Hailey-Hailey disease, immunofluorescence, Köbner phenomenon, pemphigus
Posted in Around the Globe, News and Information
Posted in Around the Globe, News and Information
A case of stable oral pemphigus vulgaris on low dose immunosuppressive therapy
The clinical and epidemiological features of pemphigus vulgaris (PV) are well documented but there remain few reports of oesophageal involvement of PV. Although previously considered to be rare, recent reports have suggested that up to 87% of patients with PV…
