Blog Archives

Pemphigus Ethnicity & ELISA Studies

By Professor Martin M Black, MD Pemphigus and its variants are rare autoimmune disorders characterized by loss of cell to cell cohesion between keratinocytes leading to intra-epidermal blistering. In all types of pemphigus, antibodies are directed against antigens in the

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What Are Autoimmune Diseases?

The word “auto” is the Greek word for self.    If a person has an autoimmune disease, the immune system mistakenly attacks itself, targeting the cells, tissues, and organs of a person’s own body. 

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Steroid-Induced Diabetes

by Christopher D. Saudek, M.D., Professor of Medicine, Johns Hopkins University School of Medicine, President, American Diabetes Association (July 2001). Steroids are commonly used in medicine, and their effects on blood sugar are often seriously underestimated. To give the bottom

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Cicatricial Pemphigoid Has Numerous Manifestations

by Dr. Joyce Rico Cicatricial pemphigoid is an autoimmune blistering disease that predominately effects mucous membranes, including the mouth and throat, eyes, and genitalia. Patients with skin involvement present with tense blisters or erosion, often on the head and neck,

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Remissions in Pemphigus

By Jean-Claude Bystryn, M.D. Professor of Dermatology Director of Immunofluorescence Laboratory The Ronald O. Perelman Department of Dermatology New York University Medical Center Pemphigus vulgaris (PV) can enter into remissions in which all manifestations of the disease disappear and all

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Companion Animals, Too, Can Get Pemphigus

by Thierry Olivry, DrVet, PhD, DipACVD, DipECVD, Associate Professor of Dermatology, Department of Clinical Sciences, College of Veterinary Medicine, NC State University, Raleigh, North Carolina, and Adjunct Clinical Associate Professor of Dermatology, Department of Dermatology, School of Medicine, University of

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Tests for Pemphigus

by Ernest H. Beutner, Ph.D.*Professor of Microbiology and Dermatology, University of Buffalo; School of Medicine and Biomedical Sciences; Buffalo, NY Patients with pemphigus may benefit by working with their doctors to gain a better understanding of the tests used to

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Why Lesions Occur at Different Sites

By Grant J. Anhalt, M.D. Johns Hopkins Dermatology I will attempt to clarify what we know about the antibody response in various forms of pemphigus and how the distribution of the targeted antigens affects the location of lesions. The synthesis

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Diagnostic Patterns and Delays in PV: Experience With 99 Patients

By David A. Sirois, D.M.D., Ph.D.Department of Oral Medicine Pemphigus vulgaris is a chronic autoimmune disease affecting the mucosa and skin and resulting in epithelial acantholysis, bullae formation, and chronic ulceration.1 Skin lesions of pemphigus vulgaris present clinically with typical

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International Survey Results

This is not a scientific study, but we can draw some conclusions that would tend to support the current statistics especially for PV. The one big difference would be the correlation between males and females. We had females returning surveys

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