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Remissions in Pemphigus

By Jean-Claude Bystryn, M.D. Professor of Dermatology Director of Immunofluorescence Laboratory The Ronald O. Perelman Department of Dermatology New York University Medical Center Pemphigus vulgaris (PV) can enter into remissions in which all manifestations of the disease disappear and all

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Companion Animals, Too, Can Get Pemphigus

by Thierry Olivry, DrVet, PhD, DipACVD, DipECVD, Associate Professor of Dermatology, Department of Clinical Sciences, College of Veterinary Medicine, NC State University, Raleigh, North Carolina, and Adjunct Clinical Associate Professor of Dermatology, Department of Dermatology, School of Medicine, University of

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Tests for Pemphigus

by Ernest H. Beutner, Ph.D.*Professor of Microbiology and Dermatology, University of Buffalo; School of Medicine and Biomedical Sciences; Buffalo, NY Patients with pemphigus may benefit by working with their doctors to gain a better understanding of the tests used to

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Why Lesions Occur at Different Sites

By Grant J. Anhalt, M.D. Johns Hopkins Dermatology I will attempt to clarify what we know about the antibody response in various forms of pemphigus and how the distribution of the targeted antigens affects the location of lesions. The synthesis

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Diagnostic Patterns and Delays in PV: Experience With 99 Patients

By David A. Sirois, D.M.D., Ph.D.Department of Oral Medicine Pemphigus vulgaris is a chronic autoimmune disease affecting the mucosa and skin and resulting in epithelial acantholysis, bullae formation, and chronic ulceration.1 Skin lesions of pemphigus vulgaris present clinically with typical

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International Survey Results

This is not a scientific study, but we can draw some conclusions that would tend to support the current statistics especially for PV. The one big difference would be the correlation between males and females. We had females returning surveys

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Development of Non-hormonal Treatment of Pemphigus

By Sergei A. Grando, MD, PhD, DSci Professor of Dermatology University of California Davis The Need for Alternative Therapies for Pemphigus. In autoimmune pemphigus, systemic glucocorticosteroid treatment is life saving but may cause severe side effects. Pemphigus patients therefore need

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Exploring the “Wildfire” World of Pemphigus Foliaceous

by Luis A. Diaz, M.D. Professor and Chairman Department of Dermatology Medical College of Wisconsin Milwaukee, Wisconsin Pemphigus foliaceous (PF) one of the major clinical variants of pemphigus, is characterized by superficial blisters and anti-epidermal autoantibodies. The epidermal antigen with

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New Perspectives on the Cause of Blister Formation

By Sergei A. Grando, M.D., Ph.D., D.Sci. Professor of Dermatology University of California Davis NPF Advisory Board Member The goal of my research is to develop a safer and more rational treatment for pemphigus. I am deeply concerned that we,

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Diagnostic Patterns in Pemphigus Vulgaris

By Dominik Ettlin, M.D., D.M.D. Northwestern University Dental School Chicago, Illinois As most readers know, the National Pemphigus Foundation held its first annual meeting in Chicago on August 1, 1998. Attendees of the meeting were given a questionnaire. The purpose

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