Pemphigus foliaceus (pem-fi-gus foli-a-shus) is an auto immune disease that affects humans and dogs and, to a lesser extent, cats and horses. In horses, it is characterized by primary lesions that often begin on the head and lower extremities; secondary…
Blog-Archive
Equine Pemphigus Foliaceus
Getagged mit: equine, horse, pemphigus, pemphigus foliaceus
Veröffentlicht unter Around the Globe, News and Information
Veröffentlicht unter Around the Globe, News and Information
Autoantibodies in Senear-Usher Syndrome: Cross-Reactivity or Multiple Autoimmunity?
Senear-Usher syndrome or pemphigus erythematosus is a pathology that overlaps clinically and serologically with pemphigus foliaceus and lupus erythematosus. Skin biopsies of patients with pemphigus erythematosus reveal acantholysis and deposits of immunoglobulins in desmosomes, and they are positive in the…
Getagged mit: autoantibodies, cross-reactivity, desmosomes, pemphigus, pemphigus erythematosus
Veröffentlicht unter Around the Globe, News and Information
Veröffentlicht unter Around the Globe, News and Information
Feline Pemphigus Foliaceus
Pemphigus foliaceus (PF) is an immune-mediated disease that causes pustules and crusted lesions, most commonly on the pinnae, nasal planum, periocular area, chin, feet of affected cats. Acantholytic cells caused by dehydration of intercellular adhesions are often seen on cytology…
Getagged mit: cat, feline, pemphigus, pemphigus foliaceus
Veröffentlicht unter Around the Globe, News and Information
Veröffentlicht unter Around the Globe, News and Information
Skin Disease, Autoimmune (Pemphigus) in Dogs
Pemphigus in Dogs Pemphigus is the general designation for a group of autoimmune skin diseases involving ulceration and crusting of the skin, as well as the formation of fluid-filled sacs and cysts (vesicles), and pus filled lesions (pustules). Some types…
Getagged mit: autoimmune, dog, pemphigus, skin
Veröffentlicht unter Around the Globe, News and Information
Veröffentlicht unter Around the Globe, News and Information
The incidence of internal malignancies in pemphigus and bullous pemphigoid in Japan.
To evaluate the significance of the association of malignancy with autoimmune blistering diseases, we studied the incidence of internal malignancies in pemphigus and bullous pemphigoid based upon 496 cases of pemphigus and 1113 cases of bullous pemphigoid in Japan. Results…
Getagged mit: bullous pemphigoid, japan, pemphigoid, pemphigus
Veröffentlicht unter Around the Globe
Veröffentlicht unter Around the Globe
Regulatory T cells in skin lesions and blood of patients with bullous pemphigoid
In BP lesional skin, immunohistochemistry and confocal microscopy were performed for CD4+, CD25+, forkhead/winged helix transcription factor (FOXP3)+, transforming growth factor (TGF)-β+ and interleukin (IL)-10+ cells. In addition, the number of CD4+CD25++FOXP3+ Tregs in peripheral blood was assessed by flow cytometry, and the…
p38MAPK inhibition prevents disease in pemphigus vulgaris mice.
Pemphigus vulgaris (PV) is a life-threatening autoimmune blistering skin disease characterized by detachment of keratinocytes (acantholysis). It has been proposed that PV IgG might trigger signaling and that this process may lead to acantholysis. Indeed, we recently identified a rapid and dose-dependent phosphorylation of p38 mitogen-activated protein kinase (p38MAPK) and…
Getagged mit: autoimmune, mice, p38MAPK, pemphigus vulgaris
Veröffentlicht unter Around the Globe, Treatment and Medication
Veröffentlicht unter Around the Globe, Treatment and Medication
Sally’s story of remission
“I have been in remission now for over 1 year (YES!!!). That is complete remission with no symtpoms and no meds. I was diagnosed in 2004 and rode the roller coaster of varying doses of prednisone coupled with Cellcept at…
Veröffentlicht unter Around the Globe
A Possible Use of Cholinergic Drugs in Pemphigus Vulgaris
Human epidermis shows a non-neuronal cholinergic system including keratinocyte (kc) acetylcholine (Ach) axis which is composed by enzymes and two families of Ach receptors (muscarinic and nicotinic receptors). The activity of these two receptors can regulate the interkeratinocytes and kcs-extracellular…
Getagged mit: acantholysis, cholinergic drugs, cholinergic system in keratinocytes cells, pemphigus vulgaris
Veröffentlicht unter Around the Globe, News and Information
Veröffentlicht unter Around the Globe, News and Information
Recognizing Pyoderma:
Although bacterial pyoderma is among the most commonly encountered dermatologic conditions in dogs, some cases present diagnostic challenges even to experienced clinicians. This article presents several unusual manifestations of pyoderma, including bullous impetigo, superficial spreading pyoderma, mucocutaneous pyoderma, and post-grooming…
Getagged mit: Bacterial culture, Bacterial overgrowth, Canine pyoderma, Cytology, Furunculosis, Impetigo, mucocutaneous, Staphylococcus
Veröffentlicht unter Around the Globe, News and Information
Veröffentlicht unter Around the Globe, News and Information
