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Equine Pemphigus Foliaceus

Pemphigus foliaceus (pem-fi-gus foli-a-shus) is an auto immune disease that affects humans and dogs and, to a lesser extent, cats and horses. In horses, it is characterized by primary lesions that often begin on the head and lower extremities; secondary

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Autoantibodies in Senear-Usher Syndrome: Cross-Reactivity or Multiple Autoimmunity?

Senear-Usher syndrome or pemphigus erythematosus is a pathology that overlaps clinically and serologically with pemphigus foliaceus and lupus erythematosus. Skin biopsies of patients with pemphigus erythematosus reveal acantholysis and deposits of immunoglobulins in desmosomes, and they are positive in the

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Feline Pemphigus Foliaceus

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Pemphigus foliaceus (PF) is an immune-mediated disease that causes pustules and crusted lesions, most commonly on the pinnae, nasal planum, periocular area, chin, feet of affected cats. Acantholytic cells caused by dehydration of intercellular adhesions are often seen on cytology

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Skin Disease, Autoimmune (Pemphigus) in Dogs

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Pemphigus in Dogs Pemphigus is the general designation for a group of autoimmune skin diseases involving ulceration and crusting of the skin, as well as the formation of fluid-filled sacs and cysts (vesicles), and pus filled lesions (pustules). Some types

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The incidence of internal malignancies in pemphigus and bullous pemphigoid in Japan.

To evaluate the significance of the association of malignancy with autoimmune blistering diseases, we studied the incidence of internal malignancies in pemphigus and bullous pemphigoid based upon 496 cases of pemphigus and 1113 cases of bullous pemphigoid in Japan. Results

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Meeting of interest

A small, but perfectly formed group of PEM Friends braved the floods in the UK on Monday 26th November 2012 to have a sociable lunch together and share their experiences of Pemphigus and Pemphigoid. Even though it was a low turnout

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Inspiration and hope for pemphigus

Pemphigus can be a tough disease to live with but many patients now in remission have found inspiration, this is Sally’s story: I have been in remission now for over 1 year (YES!!!). That is complete remission with no symptoms

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Immunohistochemistry for immunoglobulin g4 on paraffin sections for the diagnosis of pemphigus.

Context.-Pemphigus is a group of autoimmune vesiculobullous diseases characterized by immunoglobulin G (IgG) antibodies directed against desmosomal adhesion proteins, with IgG4 being the predominant subclass in active diseases. Direct immunofluorescence for IgG performed on fresh-frozen tissue plays a crucial role

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Acantholytic rosacea of the forehead and scalp in a patient with Hailey-Hailey disease

BACKGROUND: Rosacea is a common dermatosis that can involve the bald area of the scalp. We report the case of a man presenting clinical symptoms of rosacea of the forehead and the scalp, but with a histological picture of familial

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Rituximab in pemphigus

Pemphigus is a chronic, muco-cutaneous autoimmune blistering disorder; two main variants being pemphigus vulgaris (PV) and pemphigus foliaceus (PF). PV is the most common subtype, varying between 75 to 92% of total pemphigus patients. Although no community based studies are undertaken

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