Methotrexate is often used to control pemphigus and MedlinePlus lists some warnings you should be aware of. ALWAYS discuss your care with your physician before making any changes to your treatment.Methotrexate may cause very serious side effects. Some side effects of methotrexate may cause death. You should only take methotrexate to treat life-threatening cancer, or certain other conditions that are very severe and that cannot be treated with other medications. Talk to your doctor about the risks of taking methotrexate for your condition.
Read more information on Methptrexate at: http://www.nlm.nih.gov/medlineplus/druginfo/meds/a682019.html