Archivo del sitio

Acantholysis revisited: Back to basics

Acantholysis means loss of coherence between epidermal cells due to the breakdown of intercellular bridges. It is an important pathogenetic mechanism underlying various bullous disorders, particularly the pemphigus group, as well as many non-blistering disorders. Although a well-known concept, the

Etiquetado con: , , ,
Publicado en: Todo el mundo, Noticias e información

A Possible Use of Cholinergic Drugs in Pemphigus Vulgaris

Human epidermis shows a non-neuronal cholinergic system including keratinocyte (kc) acetylcholine (Ach) axis which is composed by enzymes and two families of Ach receptors (muscarinic and nicotinic receptors). The activity of these two receptors can regulate the interkeratinocytes and kcs-extracellular

Etiquetado con: , , ,
Publicado en: Todo el mundo, Noticias e información

Antidesmoglein antibodies in a patient with Hailey-Hailey disease

Abstract BACKGROUND: Hailey-Hailey disease (HHD) is a rare hereditary disease in which the genetic defect is characterized by mutation in the ATP2C1 gene coding for a transmembrane calcium pump. It is generally considered a non-immunologic acantholytic dermatosis in which direct

Etiquetado con: , , ,
Publicado en: Todo el mundo, Noticias e información

Ultrastructure of acantholysis in pemphigus foliaceus reexamined from the current perspective

Background  Pemphigus foliaceus (PF) is a chronic cutaneous autoimmune blistering disease that is characterized by superficial blistering of the skin, and according to the current perspective is caused by autoantibodies directed against desmoglein 1 (Dsg1). Objectives  To examine early acantholysis

Etiquetado con: , ,
Publicado en: Todo el mundo, Noticias e información

Pemphigus in China

By Dr. Pan Meng Pemphigus is a group of organ-specific autoimmune disorders, including pemphigus vulgaris (PV), pemphigus foliaceus (PF) and paraneoplastic pemphigus (PNP). PV is the most common disease and represents this kind of potentially life-threatening disease. It is characterized

Etiquetado con: , , , , , ,
Publicado en: Médicos

Why Lesions Occur at Different Sites

By Grant J. Anhalt, M.D. Johns Hopkins Dermatology I will attempt to clarify what we know about the antibody response in various forms of pemphigus and how the distribution of the targeted antigens affects the location of lesions. The synthesis

Etiquetado con: , , , , , , , ,
Publicado en: Médicos
UNIRSE HOY!
El registro de p y p ha sido aprobado por la Junta de revisión institucional de occidental (WIRB) y activamente es inscribir participantes.

VERSIÓN EN INGLÉS

VERSIÓN EN ESPAÑOL