A long–term study of a patient with anti-p200 pemphigoid – correlation of autoantibody levels with disease activity and an example of epitope spreading

Anti-p200 pemphigoid is a rare subepidermal blistering disease associated with autoantibodies against a 200kDa protein, reportedly corresponding to laminin γ1. However, direct evidence of the pathogenic potential of these antibodies is missing. We have followed up a patient with anti-p200…