Ultrastructure of acantholysis in pemphigus foliaceus re-examined from the current perspective

Background  Pemphigus foliaceus (PF) is a chronic cutaneous autoimmune blistering disease that is characterized by superficial blistering of the skin, and according to the current perspective is caused by autoantibodies directed against desmoglein (Dsg) 1. Objectives  To examine early acantholysis…