Roche Holding AG (ROG)’s top-selling drug Rituxan effectively cured most cases of a rare and deadly skin disease in a patient study that suggests the medicine may replace steroids as the standard treatment. In a trial among 22 people with…
Klinik für Dermatologie, Allergologie und Venerologie, Universität Lübeck, Deutschland Klinik für Dermatologie und Allergologie, Philipps-Universität Marburg, Deutschland Klinik und Poliklinik für Dermatologie und Venerologie, Universität Köln, Deutschland Klinik für Dermatologie, Technische Universität Dresden, Deutschland Abteilung Rheumatologie, LMU München, Deutschland Abteilung…
Variété de pemphigus vulgaire se caractérisant par la présence de bulles qui finissent par confluer (se rejoindre) et se rompre, créant ainsi de vastes surfaces laissant la peau à vif qui suinte et qui devient très douloureuse. Généralités Le pemphigus…
The oral cavity can be affected by a wide variety of disorders characterized by inflammation of the gingiva and/or oral mucosa. In dogs and cats, differential diagnoses for generalized oral inflammatory disorders include plaque-reactive mucositis, chronic gingivostomatitis, eosinophilic granuloma complex,…
To study associations of bullous pemphigoid (BP) with internal diseases, we conducted a retrospective case control study assessing the frequency of selected diseases – diabetes mellitus, neurological diseases, malignant tumors, benign prostate hyperplasia, hypertension and ischemic heart disease in patients…
Background: Pemphigus vulgaris was almost fatal before the advent of glucocorticoids. Unfortunately, the high doses and prolonged administration of glucocorticoids, which often needed to control the disease, result in numerous adverse effects many of which are serious. Aims: To evaluate the patients…
Background Adjuvant therapeutic methods are employed when pemphigus vulgaris (PV) fails to be controlled by conventional corticosteroid treatment. Objective: The efficacy of double filtration plasmapheresis (DFPP) was investigated in a PV patient with severe, refractory mucosal disease. Methods A total…
IMPORTANCE A rare variant of mucous membrane pemphigoid (MMP) is characterized by circulating anti-laminin 332 (Lam332) autoantibodies and seems to be associated with concurrent malignant neoplasms. OBJECTIVE To determine the prevalence and clinical significance of anti-Lam332 autoantibody detection from a large…
Pemphigus vulgaire (PV) is a paradigm of autoimmune disease affecting intercellular adhesion. The mechanisms that lead to cell–cell detachment (acantholysis) have crucial therapeutic implications and are currently undergoing major scrutiny. The first part of this review focuses on the classical…
