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Direct Immunofluorescence on Hair Follicles-Present and Future Perspectives.

Direct immunofluorescence (DIF) is an important tool for evaluating bullous autoimmune and connective tissue disorders.We report 21 cases of pemphigus vulgaris, bullous pemphigoid and lupus erythematosus that were investigated by performing DIF on scalp hair follicles. The study was done

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Publié dans Dans le monde entier, Actualités et informations

Immunopathological characteristics of patients with bullous pemphigoid and neurological disease

The relationship between bullous pemphigoid (BP) and neurological disease has been the subject of numerous recent studies and BP antigens and their isoforms have been identified in the central nervous system (CNS). Whilst epidemiological data support this association, little is

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Publié dans Dans le monde entier, Actualités et informations

Oral pemphigus vegetans: A case report.

Pemphigus is a rare vesiculobullous autoimmune disease that exhibits blistering of the skin and oral cavity. It is caused by autoantibodies directed against antigens on the surface of keratinocytes. All forms of pemphigus are associated with the presence of circulating

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Publié dans Dans le monde entier, Actualités et informations

Immunohistochemistry for immunoglobulin g4 on paraffin sections for the diagnosis of pemphigus.

Context.-Pemphigus is a group of autoimmune vesiculobullous diseases characterized by immunoglobulin G (IgG) antibodies directed against desmosomal adhesion proteins, with IgG4 being the predominant subclass in active diseases. Direct immunofluorescence for IgG performed on fresh-frozen tissue plays a crucial role

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Publié dans Dans le monde entier, Actualités et informations

Acantholytic rosacea of the forehead and scalp in a patient with Hailey-Hailey disease

BACKGROUND: Rosacea is a common dermatosis that can involve the bald area of the scalp. We report the case of a man presenting clinical symptoms of rosacea of the forehead and the scalp, but with a histological picture of familial

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Publié dans Dans le monde entier, Actualités et informations
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