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Enrichment of total serum IgG4 in patients with pemphigus

Background  Pemphigus vulgaris (PV) and pemphigus foliaceus (PF) are potentially fatal blistering diseases caused by autoantibodies targeting desmoglein (Dsg) adhesion proteins. Previous studies have shown an IgG4 > IgG1 predominance of anti-Dsg antibodies in pemphigus; Cependant, no studies have examined total serum

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Publié dans Dans le monde entier, Actualités et informations

Therapeutic effect of mizoribine on pemphigus vulgaris and pemphigus foliaceus

We evaluated the effectiveness of mizoribine, a newly developed immunosuppressive agent, as an adjuvant therapy in the treatment of both pemphigus vulgaris and pemphigus foliaceus. Eleven pemphigus patients (eight pemphigus vulgaris and three pemphigus foliaceus) received the combination therapy of

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Publié dans Dans le monde entier, Actualités et informations

Serological diagnosis of autoimmune bullous skin diseases: Prospective comparison of the BIOCHIP mosaic-based indirect immunofluorescence technique with the conventional multi-step single test strategy

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Background Various antigen-specific immunoassays are available for the serological diagnosis of autoimmune bullous diseases. Cependant, a spectrum of different tissue-based and monovalent antigen-specific assays is required to establish the diagnosis. BIOCHIP mosaics consisting of different antigen substrates allow polyvalent immunofluorescence

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Publié dans Dans le monde entier, Actualités et informations

Brazilian blood donation eligibility criteria for dermatologic patients.

A focused and commented review on the impact of dermatologic diseases and interventions in the solidary act of donating blood is presented to dermatologists to better advise their patients. This is a review of current Brazilian technical regulations on hemotherapeutic

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Publié dans Dans le monde entier, Actualités et informations

Use of modified ciclosporin in the management of feline pemphigus foliaceus: a retrospective analysis.

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Background -  Glucocorticoids as sole therapy for pemphigus foliaceus (PF) in cats are not always successful, and it is common to need additional immunomodulating agents to manage the disease. Hypothesis/Objectives -  This retrospective study evaluated the use of modified ciclosporin as an

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Publié dans Dans le monde entier, Actualités et informations, Traitement et médicaments

Enrichment of total serum IgG4 in pemphigus patients

Background:  Pemphigus vulgaris (PV) and pemphigus foliaceus (PF) are potentially fatal blistering diseases caused by autoantibodies targeting desmoglein adhesion proteins. Previous studies have shown an IgG4>IgG1 predominance of anti-desmoglein antibodies in pemphigus; Cependant, no studies have examined total serum IgG4

Tagués avec : , , ,
Publié dans Dans le monde entier, Actualités et informations

Neuromyelitis optica in a patient with pemphigus foliaceus

Neuromyelitis optica (NMO, also eponymously known as Devic’s disease) is an immune‐mediated demyelinating disease of the central nervous system that can lead to significant disability. Pediatric NMO is a rare disorder often reported after an infection. The authors report a

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Publié dans Recherche clinique, Essais cliniques, Uncategorized

Varicella-zoster virus (VZV) and alpha 1 antitrypsin: A Fatal Outcome in a patient affected by endemic pemphigus foliaceus

Herpes virus infections are well known infectious complications of pemphigus and bullous pemphigoid. We describe pathologic findings utilizing autopsy tissue from several organs from a patient affected by a new variant of endemic pemphigus in El Bagre, Colombie, South America.

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Publié dans Recherche clinique, Médical, Actualités et informations

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