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Lack of relationship between blood groups and clinical outcome (body surface area affected) in patients with pemphigus vulgaris

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Associations between blood groups and several diseases are observed in the literature. Some of these have scientific support suggesting a rationale, statistical relation. The association between ABO groups with several malignancies, hypercholesterolemia, thrombosis, myocardial infarction, duodenal ulcer, infections, and autoimmune

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Publié dans Dans le monde entier, Actualités et informations

Study of oral, ear, nose and throat involvement in pemphigus vulgaris by endoscopic examination.

Background:  Pemphigus vulgaris (PV) is an autoimmune blistering skin disorder characterized by the presence of suprabasal acantholysis and autoantibodies against desmoglein 3. There are two different clinical forms: mucocutaneous (MCPV) or mucosal (MPV). Cependant, it is not clear how PV

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Publié dans Dans le monde entier, Actualités et informations

Association between HLA-DRB1 polymorphisms and pemphigus vulgaris: a meta-analysis

Background  Several studies have reported that HLA-DRB1 may be correlated with pemphigus vulgaris (PV), but most have been based on small samples and the results remain inconsistent and unclear. Objectives  To investigate the correlation between DRB1 and PV by a

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Enrichment of total serum IgG4 in pemphigus patients

Background:  Pemphigus vulgaris (PV) and pemphigus foliaceus (PF) are potentially fatal blistering diseases caused by autoantibodies targeting desmoglein adhesion proteins. Previous studies have shown an IgG4>IgG1 predominance of anti-desmoglein antibodies in pemphigus; Cependant, no studies have examined total serum IgG4

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Pediatric Pemphigus Vulgaris: Durable Treatment Responses Achieved with Prednisone and Mycophenolate Mofetil (MMF)

This report describes the clinical presentations and treatment responses of three children with PV, as confirmed according to histology and indirect immunofluorescence studies. In all three cases, oral prednisone used in conjunction with mycophenolate mofetil (MMF) resulted in complete clinical

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Letter: Acetylcholine receptor antibodies in patients with pemphigus vulgaris: Correlation with disease extent at the time of diagnosis and during follow-up.

Several studies have tried to determine the relationship between auto-antibodies against the acetylcholine receptor and the development of pemphigus vulgaris. In this study, we observed that antibody levels against the acetylcholine receptor are mildly elevated in pemphigus vulgaris (PV), and

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Publié dans Recherche clinique

Study of Oral, Ear, Nose and Throat Involvement in Pemphigus Vulgaris by Endoscopic Examination

Background:  Pemphigus vulgaris (PV) is an autoimmune blistering skin disorder characterized by the presence of suprabasal acantholysis and autoantibodies against desmoglein 3. There are two different clinical forms: mucocutaneous (MCPV) or mucosal (MPV). Cependant, it is not clear how PV

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Publié dans Recherche clinique, Médical, Actualités et informations

Evidence for vitamin D deficiency and increased fractures’ prevalence in autoimmune bullous skin diseases.

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Diagnosis and Clinical Features of Pemphigus Vulgaris

Autoimmune bullous diseases are associated with autoimmunity against structural components that maintain cell-cell and cell-matrix adhesion in the skin and mucous membranes. They include those where the skin blisters at the basement membrane zone and those where the skin

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Have YOU Heard About ST18?

The recent buzz in the pemphigus and pemphigoid community stems from the publication ofPopulation-Specific Association between a Polymorphic Variant in ST18, Encoding a Pro-Apoptotic Molecule, and Pemphigus Vulgarisin the Journal of Investigative Dermatology (available online, Mars 2012). Despite

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