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Enrichment of total serum IgG4 in pemphigus patients

Posté le August 25, 2012 par Cristo Rey Intern

Background:  Pemphigus vulgaris (PV) and pemphigus foliaceus (PF) are potentially fatal blistering diseases caused by autoantibodies targeting desmoglein adhesion proteins. Previous studies have shown an IgG4>IgG1 predominance of anti-desmoglein antibodies in pemphigus; Cependant, no studies have examined total serum IgG4…

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