June 21-23, 2017

Organized by the International Pemphigus & Pemphigoid Foundation and the University of Lübeck Department of Dermatology.

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Overview

Conference Overview

The 2017 IPPF Scientific Conference will take place in Lübeck, Germany. It will be hosted by Dr. Sergei Grando and Dr. Detlef Zilikens.

The 2017 IPPF Scientific Conference will bring together clinical and scientific experts in the field of autoimmune bullous disorders. The conference is an opportunity for physicians and scientists from around the world to come together under the common goal of studying pemphigus and pemphigoid. This will be the first IPPF conference held outside the United States.

The goal of this conference is to identify research opportunities that will promote understanding of the causes of pemphigus and pemphigoid, as well as to provide experimental and clinical justification for novel treatment options. Conference events will begin with a welcome Reception on Wednesday night at St. Petri Church. Thursday and Friday will include presentations, abstract sessions, poster viewings, and discussion panels.

This meeting is expected to have a dramatic impact on the development of coordinated efforts among international efforts to study pemphigus and pemphigoid. We hope to generate consensus on the terminology and criteria that should be used to describe the severity of the diseases and their response to therapy.

Conference Venue

Event Venue: Media Docks

Willy-Brandt-Allee 31
23554 Lübeck
Germany

Media Docks is located in a warehouse on a peninsula in traditional Lübeck harbor. The historical, Hanseatic building was completely renovated and modernized in 2002 with steel and glass to create an exciting contrast to the original architecture.

Surrounded by water with view of the historic Old Town Island, Media Docks offers easy parking, is conveniently located near transportation options, and is only a 7-minute walk from the center of Lübeck.

Media Docks by the Numbers

  • 7 minutes to the city center
  • 15 minute walk to Lübeck Central Station
  • 1.8 km to the A1 / A20 / A21 motorway
  • 10 km to the airport Lübeck-Blankensee
  • 56 km to Hamburg / 30 minutes by car

 About Lübeck

 

From the UNESCO website

Lübeck – the former capital and Queen City of the Hanseatic League – was founded in the 12th century and prospered until the 16th century as the major trading centre for northern Europe. It has remained a centre for maritime commerce to this day, particularly with the Nordic countries. Despite the damage it suffered during the Second World War, the basic structure of the old city, consisting mainly of 15th- and 16th-century patrician residences, public monuments (the famous Holstentor brick gate), churches and salt storehouses, remains unaltered.

Find things to do in Lübeck:

Agenda

Fourth Scientific Conference of the International Pemphigus & Pemphigoid Foundation

Recent Advances in Patient-oriented Research in Pemphigus and Pemphigoid

Hosted by Dr. Sergei Grando & Dr. Detlef Zilikens

 

Wednesday, June 21, 2017

  • 4:15pm to 5:30pm Pre-IPPF Meeting of Microbiota and Genetics of Autoimmune Blistering Diseases Study Group, Library, Department of Dermatology, University of Lübeck, Ratzeburger Allee 160

Thursday, June 22, 2017

Pemphigus Diseases

  • 8:00am – 8:30am Registration
  • 8:30am – 9:00am Welcome, Conference Overview: President of the University of Lübeck – Hendrik Lehnert, Chairman of the Department of Dermatology – Detlef Zillikens, Patient representative from the Association of Pemphigus & Pemphigoid France (APPF) Laurence Gallu, Patient representative from the German Association of Pemphigus & Pemphigoid  – Rosa Maria Ober

Pemphigus I: Genetics, Clinical Presentation and Diagnosis – Chairs: Valeria Aoki, Daniel Mimouni

  • 9:00am – 9:15am Functional Genetics in Pemphigus – Dan Vodovich, Tel Aviv
  • 9:15am – 9:30am Diagnosing Pemphigus – Richard Groves, London
  • 9:30am – 9:45am Disease Scoring and Quality of Life Measurements in Pemphigus – Dedee Murrell, Sydney
  • 9:45am – 10:00am Paraneoplastic Pemphigus –  Sergei Grando, Irvine
  • 10:00am – 10:10am Abstract 1: HLA drives both activation and protection of the autoimmune response in pemphigus. Kristina Seiffert-Sinha, Buffalo
  • 10:10am – 10:20am Abstract 2: Genome-wide approach reveals novel genes and non-coding elements associated with pemphigus foliaceus. Rodrigo Coutinho de Almeida, Curitiba, Brazil
  • 10:20am – 10:45am Discussion I
  • 10:45am – 11:15am Coffee Break and Poster Viewing

Pemphigus II: Immunopathology and Treatment – Chairs: Giovanni Maria Di Zenzo, David Woodley

  • 11:15am – 11:30am Antigen-specific Therapies in Pemphigus – Aimee Payne, Philadelphia
  • 11:30am – 11:45am T-cells as Therapeutic Targets in Pemphigus – Rüdiger Eming, Marburg
  • 11:45am – 11:55am Abstract 3: Complement polymorphisms and susceptibility to pemphigus foliaceus: a possible role for a rampant proteolytic cascade in the disease. Angelica B. W. Boldt, Curitiba, Brazil
  • 11:55am – 12:05pm Abstract 4: Dsg-specific B lymphocytes and antibody production in lesion of pemphigus vulgaris patients. Meng Pan, Shanghai
  • 12:05pm – 12:25pm Discussion II
  • 12:25pm – 12:35pm Group Photo
  • 12:35pm – 2:00pm Lunch and Poster Viewing
  • 1:00pm – 2:00pm  Satellite Symposium – “The IADPO GRIP tool and how the IPPF community can benefit” Christine Janus (IADPO), IPPF & Patient Support Group Leaders 

Pemphigus III: Treatment Options – Chairs: Frédéric Caux, Branka Marinovic

  • 2:00pm – 2:15pm B cell response in pemphigus patients treated with Rituximab – Philippe Musette, Rouen
  • 2:15pm – 2:30pm The Future Role of IVIG in the Treatment of Pemphigus – Razzaque Ahmed, Boston
  • 2:30pm – 2:40pm Abstract 5: Efficacy analysis of rituximab in pemphigus over up to 68-months follow-up, Dipankar De, Chandigarh, India
  • 2:40pm – 2:50pm Abstract 6: An Oral Disease Severity Score (ODSS) validated for pemphigus vulgaris and mucous membrane pemphigoid, Martyn Ormond, London
  • 2:50pm – 3:15 Discussion III
  • 3:15pm – 3:45pm Coffee Break and Poster Viewing

Pemphigus IV: Autoantibody-mediated Effects – Chairs: Carlo Pincelli, John Stanley

  • 3:45pm – 4:00pm Autoimmunity Against Desmosomal Proteins: What Have We Learned from In Vivo Models? – Masayuki Amagai, Tokyo
  • 4:00pm – 4:15pm Autoimmunity Against Desmosomal Proteins: What Have We Learned from In Vitro Models? – Jens Waschke, Munich
  • 4:15pm – 4:30pm Signaling Pathways in Pemphigus – Eliane Muller, Bern
  • 4:30pm – 4:45pm Non-desmoglein Antibodies: What is Their Diagnostic and Payhophysiological Value? – Animesh Sinha, Buffalo
  • 4:45pm – 4:55pm Abstract 7: In vitro keratinocytes binding test for pemphigus, Federica Giurdanella, Groningen
  • 4:55pm – 5:05pm Abstract 8: Keratins regulate desmoglein binding properties via p38MAPK and are required for loss of intercellular adhesion in pemphigus, Franziska Vielmuth, Munich
  • 5:05pm – 5:15pm Abstract 9: Direct pathogenicity of anti-Desmoglein autoantibodies cloned from the IgA1 repertoire of patients with IgA pemphigus, Christoph Hammers, Philadelphia/Lübeck
  • 5:15pm – 5:25pm Global Research of the Impact of Dermatological Diseases – Christine Janus, Ottawa
  • 5:25pm – 6:00pm Discussion IV

Friday, June 23, 2017

Pemphigoid Diseases

Pemphigoid I: Epidemiology, Clinical Presentation and Diagnosis – Chairs: José Mascaro, John Zone

  • 8:30am – 8:45am Comorbidities in Bullous Pemphigoid – Kasai Tasanen, Oulu
  • 8:45am – 9:00am New Clinical Variants of Bullous Pemphigoid – Lucca Borradori, Bern
  • 9:00am – 9:15am Diagnosis of Pemphigoid Diseases – Marcel Jonkman, Groningen
  • 9:15am – 9:30am Mucous Membrane Pemphigoid – John Dart, London
  • 9:30am – 9:40am Abstract 10: Eosinophil Cationic Protein (ECP), a predictive marker of bullous pemphigoid severity and outcome, Frank Antonicelli, Reims
  • 9:40am – 9:50am Abstract 11: Optimal technical procedure for serration pattern analysis in direct immunofluorescence microscopy, Joost M. Meijer, Groningen
  • 9:50am – 10:00am Abstract 12: Idiopathic linear IgA bullous dermatosis: clinical, immunological, and prognostic factors based on a case series of 72 adults, Catherine Prost Squarcioni, Bobigny, Université Paris 13
  • 10:00am – 10:30am Discussion I
  • 10:30am – 11:00am Coffee Break and Poster Viewing

Pemphigoid II: Disease Pathways and Mechanisms – Chairs: Russel Hall, Takashi Hashimoto

  • 11:00am – 11:15am Mechanisms of Effector Cell Recruitment – Christian SadikLübeck
  • 11:15am – 11:30am Contributions of cytokines – Frank Antonicelli, Reims
  • 11:30am – 11:45am Fc-independent Mechanisms – Wataru Nishie, Sapporo
  • 11:45am – 12:00pm Cell Signaling – Ralf LudwigLübeck
  • 12:00pm – 12:10pm Abstract 13: A single mutation in mitochondrially-encoded complex V gene (mt-Atp8) reduces severity of autoimmune skin blistering disease in mice, Paul Schilf, Lübeck
  • 12:10pm – 12:20pm Abstract 14: Regulatory T cells suppress the myeloid cell-dependent inflammation and blistering in pemphigoid diseases, Katja Bieber, Lübeck
  • 12:20pm – 12:30pm Abstract 15: Neutrophil adhesion enables antibody-mediated proteolytical tissue damage, Xinhua Yu, Borstel
  • 12:30pm – 1:00pm Discussion II
  • 1:00pm – 2:00pm Poster Session with Lunch

Pemphigoid III: Treatment Options – Chairs: Pascal Joly, Jane Setterfield

  • 2:00pm – 2:15pm IgE-mediated Mechanisms in Bullous Pemphigoid – Janet Fairley, Iowa
  • 2:15pm – 2:30pm Controlled Treatment Trials in Bullous Pemphigoid – Karen Harman, Leicester
  • 2:30pm – 2:45pm Emerging Treatments of Bullous Pemphigoid – Enno SchmidtLübeck
  • 2:45pm – 2:55pm Abstract 16: Association of high serum anti-BP180 IgE and IgG levels with increased mortality in the prospective multicenter Bullous Pemphigoid Steroids and Tetracyclines (BLISTER) trial, Maike M. Holtsche, Lübeck
  • 2:55pm – 3:05pm Abstract 17: B cell-depleting therapy for a long term control of mucous membrane pemphigoid, Giuseppe Cianchini, Rome
  • 3:05pm – 3:15pm Abstract 18: TNT009, an inhibitor of the classical pathway, inhibits C3d deposition at the dermal-epidermal junction in patients with bullous pemphigoid, Sandip Panicker, South San Franciso
  • 3:15pm – 3:45pm Discussion III
  • 3:45pm – 4:00pm Farewell remarks and poster awards
  • 4:00pm – 4:15pm Coffee Break
  • 4:15pm – 5:45pm Post-IPPF Consensus Meeting: Practical Treatment of Bullous Pemphigoid

*This agenda is subject to change.

Social Program

Wednesday, June 21, 2017

  • 6:30pm to 10:00pm Welcome Reception at St. Petri Church
  • 7:00pm to 7:30pm Congress opening and words of welcome

Pastor of the St. Petri Church – Pastor Bernd Schwarze
IPPF Scientific Conference Co-Chairs – Detlef Zillikens, Sergei Grando
IPPF Executive Director – Marc Yale
Piano and Guitar – Sven Alexander Rieper and Andreas Lukas Glaser

Thursday, June 22, 2017

  • 6:15pm River Cruise Around Medieval City
  • 7:30pm Networking Evening, Gemeinnützige
Travel & Hotel Information

Travel

Hamburg International Airport

Lübeck is 60km from Hamburg International Airport, and it is accessible by train, bus, or taxi.

Traveling from Hamburg International Airport to Lübeck by Train:

From the Underground in Terminal 1, take the S1 line from Hamburg Airport to Hamburg Main Railway Station (Hamburg Hbf or Hamburg Hauptbahnhof) Trains run every 10 minutes. The trip to Hamburg Hbf is approximately 24 minutes.

From Hamburg Main Railway Station (Hamburg Hbf), take the train directly to Lübeck Central Railway Station (Lübeck Hbf). The trip from Hamburg Hbf to Lübeck Hbf is approximately 45 minutes. It is advised to purchase the ticket at the Hamburg Airport station using the automatic ticket machine. On the touch screen, choose Schleswig-Holstein-Tarif, enter Lübeck in the destination field, and the next available trains will be displayed. The best choice is the RE train, which costs around 14 EUR for a single journey. This ticket covers the entire stretch from Hamburg Airport to Lübeck Central Railway Station (Lübeck Hbf).

Subway/Rapid Transit Rail Information: S-Bahn Hamburg and Hamburg Airport Travel Information

Regional Rail Information: German Rail

Bus Information: Hamburg Airport Travel Information

Hamburg Transport Association (HVV): http://www.hvv.de/

From Lübeck Central Railway Station to the University or Town Centre by Bus

When exiting the Lübeck Central Railway Station (Lübeck Hbf), the Central Bus Station (ZOB) is across the street after passing through a small passageway. There are several bus lines that go directly to the University (all bus lines pass the Town Centre):

  • Line 1 with the direction Hochschulstadtteil or Line 9 with the direction Grillenweg: get off at Fachhochschule and cross the street to enter the campus
  • Line 6 with the direction Blankenseer Dorfplatz or Line 4 with the direction Groß Grönau: get off at the stop Universität.

A single journey takes about 17 minutes. Your train ticket is valid for the bus travel on that day. You do not need to purchase extra tickets on the bus.

By Car

Media Docks is located at Willy-Brandt-Allee 31, 23554 Lübeck. If your navigation device does not find the road, you can alternatively use the following coordinates: 53.874456 (latitude) and 10.684093 (longitude).

Parking is available in sufficient quantity.

Hotel

The IPPF has secured three hotels with a limited number of rooms at a discounted rate. The following hotels can be booked on a first-come, first-serve basis by email or phone using the included booking code:

The following is a list of hotels also within walking distance of the conference:

Abstract Submission

Abstract Submission Template

Please use our template for abstract submissions:

Submission Address

Send all abstracts to: IPPF2017@uksh.de

Deadline

The deadline for abstract submission is April 17, 2017.

Guidelines for Oral Presentation (selected from submitted abstract):

Each presentation is allocated 7 minutes followed by 3 minutes discussion. These time restrictions will have to be followed strictly in the interest of all presenters. The presentations should be given in English. Projection of the presentations is made by beamer (beamer in 16.9 size). Please bring your presentation on USB stick as power point presentation. Please note that due to technical reasons only PC presentations that can be opened by MS Office can be used. All presentations have to be turned in at least 30 minutes prior to each session.

Please prepare the poster according to the following instructions:

Poster size: max. 90 cm width, max. 150 cm height. We are asking all first authors or another designated co-author to be present during the assigned poster sessions to allow vivid exchange during the poster session.

Thank You to our Partners:

Sponsoring

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