by Edward Tenner, M.D. INTRODUCTION The autoimmune bullous skin diseases, pemphigus (with major subsets pemphigus vulgaris, pemphigus foliaceus and paraneoplastic pemphigus) and the more common bullous pemphigoid (with variant disease phenotypes of cicatricial pemphigoid and gestational pemphigoid) each may have…
ארכיון הבלוג
Pemphigus in China
By Dr. Pan Meng Pemphigus is a group of organ-specific autoimmune disorders, including pemphigus vulgaris (PV), pemphigus foliaceus (PF) and paraneoplastic pemphigus (PNP). PV is the most common disease and represents this kind of potentially life-threatening disease. It is characterized…
עם התגית: acantholysis, azathioprine, cyclophosphamide, glucocorticoids, histopathology, immunosuppressant, paraneoplastic
נשלח ב Medical
נשלח ב Medical
Treating Pemphigus with Immunoglobulin (IVIG) Therapy
By Peggy Clinton, BSN, Eric Hill, Wanda Rogers, RPH As many of you know, Pemphigus is an immune-mediated blistering skin disease involving the IgG autoantibodies which bind to the cell wall of the epidermis. The specific pathway of the blistering…
עם התגית: corticosteroid, cyclophosphamide, immunodermatology, immunosuppressant, intramuscularly, supplementation
נשלח ב Medical
נשלח ב Medical
Cicatricial Pemphigoid Has Numerous Manifestations
by Dr. Joyce Rico Cicatricial pemphigoid is an autoimmune blistering disease that predominately effects mucous membranes, including the mouth and throat, eyes, and genitalia. Patients with skin involvement present with tense blisters or erosion, often on the head and neck,…
עם התגית: antiinflammatory, autoantibodies, cyclophosphamide, dermatology, gynecologists, intralesional, manifestation, ophthalmologists, otolaryngologists
נשלח ב Medical
נשלח ב Medical
Remissions in Pemphigus
By Jean-Claude Bystryn, M.D. Professor of Dermatology Director of Immunofluorescence Laboratory The Ronald O. Perelman Department of Dermatology New York University Medical Center Pemphigus vulgaris (PV) can enter into remissions in which all manifestations of the disease disappear and all…
Companion Animals, Too, Can Get Pemphigus
by Thierry Olivry, DrVet, PhD, DipACVD, DipECVD, Associate Professor of Dermatology, Department of Clinical Sciences, College of Veterinary Medicine, NC State University, Raleigh, North Carolina, and Adjunct Clinical Associate Professor of Dermatology, Department of Dermatology, School of Medicine, University of…
New Perspectives on the Cause of Blister Formation
By Sergei A. Grando, M.D., Ph.D., D.Sci. Professor of Dermatology University of California Davis NPF Advisory Board Member The goal of my research is to develop a safer and more rational treatment for pemphigus. I am deeply concerned that we,…
Bullous Disease Treatment
Grant J. Anhalt, MD Head, Dermatoimmunology Department Johns Hopkins University Baltimore, Maryland Vice President in charge of Scientific Affairs, The International Pemphigus Foundation
Prior to the introduction of an effective therapy with oral corticosteroids in the 1950s, the disease had a dismal natural course with a 50% mortality rate at 2 years and 100%
