Abstract BACKGROUND: Hailey-Hailey disease (HHD) is a rare hereditary disease in which the genetic defect is characterized by mutation in the ATP2C1 gene coding for a transmembrane calcium pump. It is generally considered a non-immunologic acantholytic dermatosis in which direct…
Archivio Mensile: December 2012
Antidesmoglein antibodies in a patient with Hailey-Hailey disease
Taggato con: acantholysis, antidesmoglein antibodies, Hailey-Hailey disease, transmembrane calcium pump
Pubblicato in Around the Globe, News and Information
Pubblicato in Around the Globe, News and Information
Acantholytic rosacea of the forehead and scalp in a patient with Hailey-Hailey disease
BACKGROUND: Rosacea is a common dermatosis that can involve the bald area of the scalp. We report the case of a man presenting clinical symptoms of rosacea of the forehead and the scalp, but with a histological picture of familial…
Taggato con: Acantholytic rosacea, Hailey-Hailey disease, immunofluorescence, Köbner phenomenon, pemphigus
Pubblicato in Around the Globe, News and Information
Pubblicato in Around the Globe, News and Information
A case of stable oral pemphigus vulgaris on low dose immunosuppressive therapy
The clinical and epidemiological features of pemphigus vulgaris (PV) are well documented but there remain few reports of oesophageal involvement of PV. Although previously considered to be rare, recent reports have suggested that up to 87% of patients with PV…
Taggato con: azathioprine, immunosuppression, mucocutaneous, oesophageal lesions, OESOPHAGUS, pemphigus vulgaris, prednisolone, UPPER GASTROINTESTINAL SYMPTOMS
Pubblicato in Around the Globe, News and Information
Pubblicato in Around the Globe, News and Information
Pemphigus foliaceus masquerading as IgA pemphigus and responding to dapsone
A 14-year-old male presented with seven years history of recurrent episodes of fluid filled, itchy and eroded lesions over the body not responding to oral corticosteroids and azathioprine. Dermatological examination revealed crusted plaques and erosions in a seborrheic distribution. Histopathology…
Taggato con: azathioprine, desmologlein, dexamethason, immunofluorescent, pemphigus foliaceus
Pubblicato in Around the Globe, News and Information
Pubblicato in Around the Globe, News and Information
Findings around hair follicles and sweat glands in immunobullous disease
Background Inherent to some immunobullous disorders is potential for intraepidermal or dermal–epidermal junction fragility, a phenomenon that may compromise biopsy specimen integrity and direct immunofluorescence (DIF) interpretation. In these situations, cutaneous adnexal structures (e.g. hair follicles, sweat apparatus) usually remain…
Taggato con: adnexal diseases, hair follicle, immunobullous disorders, immunofluorescence technique, sweat glands
Pubblicato in Around the Globe, News and Information
Pubblicato in Around the Globe, News and Information
