Pemphigus is a rare autoimmune blistering disease with different phenotypes. The evaluation of therapeutic interventions requires a reliable, valid and feasible to use measurement. However, there is no gold standard to measure the disease activity in clinical trials. In this…
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Oral Inflammation in Small Animals
The oral cavity can be affected by a wide variety of disorders characterized by inflammation of the gingiva and/or oral mucosa. In dogs and cats, differential diagnoses for generalized oral inflammatory disorders include plaque-reactive mucositis, chronic gingivostomatitis, eosinophilic granuloma complex,…
Taggato con: Canine, cat, chronic gingivostomatitis, dog, eosinophilic granuloma complex, erythema multiforme, feline, pemphigoid, pemphigus
Pubblicato in Around the Globe, News and Information
Pubblicato in Around the Globe, News and Information
The frequency of osteoporosis in patients with pemphigus vulgaris on treatment
Background: Pemphigus vulgaris was almost fatal before the advent of glucocorticoids. Unfortunately, the high doses and prolonged administration of glucocorticoids, which often needed to control the disease, result in numerous adverse effects many of which are serious. Aims: To evaluate the patients…
Taggato con: glucocorticoids, osteoporosis, pemphigus
Pubblicato in Around the Globe, News and Information
Pubblicato in Around the Globe, News and Information
Desmosomal adhesion and pemphigus vulgaris: the first half of the story
Pemfigo volgare (PV) is a paradigm of autoimmune disease affecting intercellular adhesion. The mechanisms that lead to cell–cell detachment (acantholysis) have crucial therapeutic implications and are currently undergoing major scrutiny. The first part of this review focuses on the classical…
Oxidative stress and autoimmune skin disease.
Antioxidants play the important role in our body of neutralizing free radicals and peroxides that are formed during normal physiologic events. While these reactive oxygen species are necessary for numerous biological processes, when created in excess they can have deleterious…
Taggato con: alopecia areata, Oxidative stress, pemphigus, pemphigus vulgaris, psoriasis, vitiligo
Pubblicato in Around the Globe, News and Information
Pubblicato in Around the Globe, News and Information
Lobar torsion after lung transplantation
Lobar torsion is a rare complication after lung transplantation. Here we report a case of right middle lobe (RML) torsion after bilateral sequential lung transplantation (BLTx). This 30-year-old lady underwent BLTx for bronchiolitis obliterans due to paraneoplastic pemphigus. The right…
Taggato con: extracorporeal membrane oxygenation, lung transplantation, pemphigus, torsion abnormality
Pubblicato in Around the Globe, News and Information
Pubblicato in Around the Globe, News and Information
Drug-triggered pemphigus foliaceus
Pemphigus foliaceus (PF) is the most common autoimmune skin disease of dogs and other animal species. Although PF can spontaneously affect dogs of any breed, it appears more prevalent in Akita Inus and chow chows in the United States. The…
Endemic pemphigus in the peruvian Amazon: epidemiology and risk factors for the development of complications during treatment
BACKGROUND: Pemphigus is an autoimmune blistering disease. According to a report, in areas of endemic pemphigus foliaceus (EPF) in Peru there are cases of pemphigus vulgaris with epidemiologic, clinical and histopathologic characteristics similar to those of “endemic pemphigus vulgaris” (EPV) in…
Pemphigus foliaceus masquerading as IgA pemphigus and responding to dapsone
A 14-year-old male presented with seven years history of recurrent episodes of fluid filled, itchy and eroded lesions over the body not responding to oral corticosteroids and azathioprine. Dermatological examination revealed crusted plaques and erosions in a seborrheic distribution. Histopathology…
Taggato con: Dapsone, IgA, IgA pemphigus, pemphigus, pemphigus foliaceus
Pubblicato in Around the Globe, News and Information
Pubblicato in Around the Globe, News and Information
Clinical Relevance of Autoantibodies in Patients with Autoimmune Bullous Dermatosis
The authors present their experience related to the diagnosis, trattamento, and followup of 431 patients with bullous pemphigoid, 14 patients with juvenile bullous pemphigoid, and 273 patients with pemphigus. The detection of autoantibodies plays an outstanding role in the diagnosis…
Taggato con: autoantibodies, autoimmune, bullous dermatosis, bullous pemphigoid, IgA pemphigoid, pemphigoid, pemphigus, pemphigus vulgaris
Pubblicato in Around the Globe, News and Information
Pubblicato in Around the Globe, News and Information
