A Study to Evaluate the Intra-rater and Inter-rater reliability of the Pemphigus Disease Area Index (PDAI) and the Autoimmune Bullous Skin Disorder Intensity Score (ABSIS) for Use by Dermatologists To download and print the Informed Consent Form, click HERE. (You will…
年別アーカイブ: 2007
The use of KC706 for the Treatment of Pemphigus Vulgaris
The purpose of this trial is to (a) determine the ability of KC706 to prevent the appearance of new blisters and heal existing blisters, while maintaining stable doses of corticosteroids and/or immunosuppressants, in patients with pemphigus vulgaris (b) to determine…
カテゴリー: 臨床試験
“Paging Doctor Howard, Doctor Fine, Doctor Howard…”
Save the Comedy Routines for TV; Find the Doctor That is Right for You The title comes from the Three Stooges’ short “Men in Black” (1934), in which the trio play doctors. The short, a parody of MGM’s Clark Cable…
カテゴリー: Medical
NYU: Is IVIg Effectiveness Improved by the Concurrent Administration of Cyclophosphamide
The purpose of the trial is to determine whether the effectiveness of IVIg is improved by the concurrent administration of cyclophosphamide. There is evidence that it can, but a formal randomized trial is required to be sure.
カテゴリー: 臨床試験
Regulatory T Cells Are Severely Reduced in PV
This new study, published in the journal "Dermatology", shows that a severe reduction of T (Treg) cells may be involved in the pathogenesis of pemphigus vulgaris (PV), an autoimmune blistering disease.
カテゴリー: Medical
Keratoprosthesis steadily gaining ground on corneal grafting, surgeons say
PHILADELPHIA — Permanent keratoprosthesis is becoming a viable and popular alternative to corneal transplantation, according to two specialists speaking here at the 2007 Wills Eye Hospital Annual Alumni Conference.
カテゴリー: Medical
Loss of Control: Your Choice
No one asks to be “chosen” for chronic illness and/or pain. There are, however, choices you can make which can either empower you or allow you to be a victim of circumstances. Not feeling you are in total control does not…
カテゴリー: Health and Lifestyle
Rituximab: A New Treatment for Recalcitrant PV?
Rituximab (RTX) is anti-CD20 chimeric antibody that selectively targets B cells. CD20 is a molecule that functions as an antigen for it. CD20 is expressed on mature antibody producing B cells, but not on plasma cells.(1) The FDA has approved…
カテゴリー: Medical
Anti-TNF Therapy for Mucous Membrane Pemphigoid
Mucous Membrane Pemphigoid, also known as Cicatricial Pemphigoid, is a serious autoimmune blistering disorder that can result in blindness and other complications as the result of scarring of the mucous membranes. To our knowledge, there have been 2 reported uses…
カテゴリー: Medical
Stanford: Etanercept (Enbrel) to Treat Pemphigus Vulgaris
The primary endpoint is to determine the number of days it takes to achieve a 50% reduction in blister count, and secondary endpoints include a reduction of baseline prednisone dose once the primary endpoint has been achieved. The trial will…
カテゴリー: 臨床試験
