To study associations of bullous pemphigoid (BP) with internal diseases, we conducted a retrospective case control study assessing the frequency of selected diseases – diabetes mellitus, neurological diseases, malignant tumors, benign prostate hyperplasia, hypertension and ischemic heart disease in patients…
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Bullous pemphigoid and internal diseases – A case-control study.
태그됨： bullous pemphigoid, cancer, diabetes mellitus, etiopathogenesis, neurological disorder
전세계, 뉴스 및 정보 에 올린 글
전세계, 뉴스 및 정보 에 올린 글
Metformin in dermatology: an overview.
For several decades, metformin has been used as an oral hypoglycaemic agent, where it is the first line of treatment in overweight and obese type 2 diabetic patients. This is because it decreases the hepatic glucose output and acts as…
Clinical Relevance of Autoantibodies in Patients with Autoimmune Bullous Dermatosis
The authors present their experience related to the diagnosis, 치료, and followup of 431 patients with bullous pemphigoid, 14 patients with juvenile bullous pemphigoid, and 273 patients with pemphigus. The detection of autoantibodies plays an outstanding role in the diagnosis…
Biochip Technology for the Serological Diagnosis of Bullous Pemphigoid
Bullous pemphigoid is an autoimmune blistering skin disease characterized by the presence of circulating autoantibodies which recognize specific proteins of the epidermis and dermoepidermal junction. Diagnosis is based on clinical criteria and laboratory investigations, notably histology, direct and indirect immunofluorescence,…
태그됨： anti-BP180, anti-BP230, antigen, autoantibodies, biochip, bullous pemphigoid, 엘리 사
전세계, 뉴스 및 정보, Technolgy 에 올린 글
전세계, 뉴스 및 정보, Technolgy 에 올린 글
The incidence of internal malignancies in pemphigus and bullous pemphigoid in Japan.
To evaluate the significance of the association of malignancy with autoimmune blistering diseases, we studied the incidence of internal malignancies in pemphigus and bullous pemphigoid based upon 496 cases of pemphigus and 1113 cases of bullous pemphigoid in Japan. Results…
Regulatory T cells in skin lesions and blood of patients with bullous pemphigoid
In BP lesional skin, immunohistochemistry and confocal microscopy were performed for CD4+, CD25+, forkhead/winged helix transcription factor (FOXP3)+, transforming growth factor (TGF)-β+ and interleukin (IL)-10+ cells. In addition, the number of CD4+CD25++FOXP3+ Tregs in peripheral blood was assessed by flow cytometry, and the…
Concurrence of bullous pemphigoid and herpetiform pemphigus with IgG antibodies to desmogleins 1/3 and desmocollins 1-3.
MADAM, Autoantibodies in pemphigus target preferentially desmoglein 1 (Dsg1) and Dsg3, and rarely desmocollins 1-3 (Dsc1-3). Pemphigus herpetiformis (PH) is one of pemphigus subtypes and characterized by pruritic annular erythemas with vesicles in the periphery, rarity of mucosal involvement and…
Concurrence of bullous pemphigoid and herpetiform pemphigus with IgG antibodies to desmogleins 1/3 and desmocollins 1-3
MADAM, Autoantibodies in pemphigus target preferentially desmoglein 1 (Dsg1) and Dsg3, and rarely desmocollins 1-3 (Dsc1-3). Pemphigus herpetiformis (PH) is one of pemphigus subtypes and characterized by pruritic annular erythemas with vesicles in the periphery, rarity of mucosal involvement and…
Autoantibody detection in bullous pemphigoid: Clinical evaluation of the EUROPLUS™ Dermatology Mosaic.
Bullous pemphigoid (BP) is an autoimmune blistering skin disease. Autoantibodies to BP180 and BP230 can be detected by indirect immunofluorescence (IIF) on different substrates (oesophagus, salt-split-skin, BP180-antigen dots, BP230-transfected cells) and ELISA. Here, we compared test characteristics of these test…
Diagnostic accuracy of enzyme-linked immunosorbent assays (엘리 사) to detect anti-skin autoantibodies in autoimmune blistering skin diseases: A systematic review and meta-analysis.
Abstract BACKGROUND: Systematic reviews and meta-analysis are essential tools to accurately and reliably summarize evidence, and can be used as a starting point for developing practice guidelines for the diagnosis and treatment of patients. AIM: To estimate the diagnostic accuracy…
