The molecular basis of disease heterogeneity in autoimmune conditions such as Pemphigus vulgaris is poorly understood. Although desmoglein 3 (Dsg3) has been well established as a primary target of immunoglobulin (Ig) autoantibodies in PV, there remain several questions regarding the…
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Specific immunoglobulin isotypes correlate with disease activity, morphology, duration and HLA association in Pemphigus vulgaris.
태그됨： autoantibodies, desmoglein 3, HLA, IgG1, IgG4, immunoglobulin, isotype, pemphigus vulgaris
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Rituximab in pemphigus
Pemphigus is a chronic, muco-cutaneous autoimmune blistering disorder; two main variants being pemphigus vulgaris (PV) and pemphigus foliaceus (PF). PV is the most common subtype, varying between 75 to 92% of total pemphigus patients. Although no community based studies are undertaken…
태그됨： corticosteroid, DCP, IgG1, immunosuppressant, MabThera, pemphigus, pemphigus foliaceus, pemphigus vulgaris, rituxmab
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전세계, 뉴스 및 정보 에 올린 글
