OBJECTIVES: Hailey-Hailey disease (HHD), or benign familial pemphigus, is a rare autosomal dominant genodermatosis characterized by the formation of blisters. Eruptions are usually located in large skin folds, and when blisters become infected the condition can be very painful and disabling.…
Carbon Dioxide Laser Treatment in Hailey-Hailey Disease: A Series of 8 Patients.
Tagged with: carbon dioxide, Hailey-Hailey disease, laser
Posted in Around the Globe, Treatment and Medication
Posted in Around the Globe, Treatment and Medication
Lobar torsion after lung transplantation
Lobar torsion is a rare complication after lung transplantation. Here we report a case of right middle lobe (RML) torsion after bilateral sequential lung transplantation (BLTx). This 30-year-old lady underwent BLTx for bronchiolitis obliterans due to paraneoplastic pemphigus. The right…
Tagged with: extracorporeal membrane oxygenation, lung transplantation, pemphigus, torsion abnormality
Posted in Around the Globe, News and Information
Posted in Around the Globe, News and Information
Drug-triggered pemphigus foliaceus
Pemphigus foliaceus (PF) is the most common autoimmune skin disease of dogs and other animal species. Although PF can spontaneously affect dogs of any breed, it appears more prevalent in Akita Inus and chow chows in the United States. The…
Endemic pemphigus in the peruvian Amazon: epidemiology and risk factors for the development of complications during treatment
BACKGROUND: Pemphigus is an autoimmune blistering disease. According to a report, in areas of endemic pemphigus foliaceus (EPF) in Peru there are cases of pemphigus vulgaris with epidemiologic, clinical and histopathologic characteristics similar to those of “endemic pemphigus vulgaris” (EPV) in…
Metformin in dermatology: an overview.
For several decades, metformin has been used as an oral hypoglycaemic agent, where it is the first line of treatment in overweight and obese type 2 diabetic patients. This is because it decreases the hepatic glucose output and acts as…
Tagged with: bullous pemphigoid, leukocytoclastic vasculitis, lichen planus, psoriasiform drug eruption
Posted in Around the Globe, News and Information
Posted in Around the Globe, News and Information
Pemphigus foliaceus masquerading as IgA pemphigus and responding to dapsone
A 14-year-old male presented with seven years history of recurrent episodes of fluid filled, itchy and eroded lesions over the body not responding to oral corticosteroids and azathioprine. Dermatological examination revealed crusted plaques and erosions in a seborrheic distribution. Histopathology…
Tagged with: Dapsone, IgA, IgA pemphigus, pemphigus, pemphigus foliaceus
Posted in Around the Globe, News and Information
Posted in Around the Globe, News and Information
Acantholysis revisited: Back to basics
Acantholysis means loss of coherence between epidermal cells due to the breakdown of intercellular bridges. It is an important pathogenetic mechanism underlying various bullous disorders, particularly the pemphigus group, as well as many non-blistering disorders. Although a well-known concept, the…
Tagged with: acantholysis, Nikolsky′s sign, primary, secondary
Posted in Around the Globe, News and Information
Posted in Around the Globe, News and Information
Clinical Relevance of Autoantibodies in Patients with Autoimmune Bullous Dermatosis
The authors present their experience related to the diagnosis, treatment, and followup of 431 patients with bullous pemphigoid, 14 patients with juvenile bullous pemphigoid, and 273 patients with pemphigus. The detection of autoantibodies plays an outstanding role in the diagnosis…
Tagged with: autoantibodies, autoimmune, bullous dermatosis, bullous pemphigoid, IgA pemphigoid, pemphigoid, pemphigus, pemphigus vulgaris
Posted in Around the Globe, News and Information
Posted in Around the Globe, News and Information
Paraneoplastic Pemphigus: A Paraneoplastic Autoimmune Multiorgan Syndrome or Autoimmune Multiorganopathy?
Paraneoplastic pemphigus (PNP), a clinically and immunopathologically distinct mucocutaneous blistering dermatosis, is a severe form of autoimmune multiorgan syndrome generally associated with poor therapeutic outcome and high mortality. This IgG-mediated disease is initiated by an obvious or occult lymphoproliferative disorder…
Tagged with: autoimmune, paraneoplastic pemphigus, pemphigus, PNP
Posted in Around the Globe, News and Information
Posted in Around the Globe, News and Information
Localized pemphigus with vegetative features
We present a 58-year-old Jamaican man with an eight-month history of an isolated, vegetative, eroded, and crusted plaque on the posterior aspect of the scalp. One month prior to referral to the Charles C. Harris Skin and Cancer Pavilion he…
Tagged with: IgG, Jamaica, localized pemphigus, pemphigus, pemphigus vulgaris, vegetative
Posted in Around the Globe, News and Information
Posted in Around the Globe, News and Information
