IMPORTANCE A rare variant of mucous membrane pemphigoid (MMP) is characterized by circulating anti-laminin 332 (Lam332) autoantibodies and seems to be associated with concurrent malignant neoplasms. OBJECTIVE To determine the prevalence and clinical significance of anti-Lam332 autoantibody detection from a large…
Jaarlijks archief: 2013
Prevalence and Clinical Significance of Anti-Laminin 332 Autoantibodies Detected by a Novel Enzyme-Linked Immunosorbent Assay in Mucous Membrane Pemphigoid
Getagd met Anti-Laminin 332, autoantibodies, Autoimmune bullous diseases
Geplaatst in Around the Globe, News and Information
Geplaatst in Around the Globe, News and Information
Desmosomal adhesion and pemphigus vulgaris: the first half of the story
Pemphigus vulgaris (PV) is a paradigm of autoimmune disease affecting intercellular adhesion. The mechanisms that lead to cell–cell detachment (acantholysis) have crucial therapeutic implications and are currently undergoing major scrutiny. The first part of this review focuses on the classical…
Oxidative stress and autoimmune skin disease.
Antioxidants play the important role in our body of neutralizing free radicals and peroxides that are formed during normal physiologic events. While these reactive oxygen species are necessary for numerous biological processes, when created in excess they can have deleterious…
Getagd met alopecia areata, Oxidative stress, pemphigus, pemphigus vulgaris, psoriasis, vitiligo
Geplaatst in Around the Globe, News and Information
Geplaatst in Around the Globe, News and Information
Application for Tacrolimus Ointment in Treating Refractory Inflammatory Ocular Surface Diseases
Purpose To evaluate the therapeutic effects of topical tacrolimus ointment on refractory inflammatory ocular surface diseases. Design Retrospective interventional consecutive case series. Methods In Severance Hospital, Seoul, South Korea, 0.02% tacrolimus ointment was topically applied 1 to 3 times per…
Getagd met refractory inflammatory ocular surface diseases, steroid, Tacrolimus Ointment
Geplaatst in Around the Globe, News and Information
Geplaatst in Around the Globe, News and Information
An attempt to develop mouse model for anti-laminin γ1 pemphigoid.
BACKGROUND: We recently reported that the autoantibodies of anti-p200 pemphigoid sera react with laminin γ1 and renamed this entity as anti-laminin γ1 pemphigoid. However, it has not been clarified whether the anti-laminin γ1 autoantibodies, particularly those to the C-terminal integrin binding…
Getagd met anti-laminin, bunny, mice, mouse, rabbit
Geplaatst in Around the Globe, News and Information
Geplaatst in Around the Globe, News and Information
Carbon Dioxide Laser Treatment in Hailey-Hailey Disease: A Series of 8 Patiënten.
OBJECTIVES: Hailey-Hailey disease (HHD), or benign familial pemphigus, is a rare autosomal dominant genodermatosis characterized by the formation of blisters. Eruptions are usually located in large skin folds, and when blisters become infected the condition can be very painful and disabling.…
Getagd met carbon dioxide, Hailey-Hailey disease, laser
Geplaatst in Around the Globe, Treatment and Medication
Geplaatst in Around the Globe, Treatment and Medication
Lobar torsion after lung transplantation
Lobar torsion is a rare complication after lung transplantation. Here we report a case of right middle lobe (RML) torsion after bilateral sequential lung transplantation (BLTx). This 30-year-old lady underwent BLTx for bronchiolitis obliterans due to paraneoplastic pemphigus. The right…
Getagd met extracorporeal membrane oxygenation, lung transplantation, pemphigus, torsion abnormality
Geplaatst in Around the Globe, News and Information
Geplaatst in Around the Globe, News and Information
Drug-triggered pemphigus foliaceus
Pemphigus foliaceus (PF) is the most common autoimmune skin disease of dogs and other animal species. Although PF can spontaneously affect dogs of any breed, it appears more prevalent in Akita Inus and chow chows in the United States. The…
Endemic pemphigus in the peruvian Amazon: epidemiology and risk factors for the development of complications during treatment
BACKGROUND: Pemphigus is an autoimmune blistering disease. According to a report, in areas of endemic pemphigus foliaceus (EPF) in Peru there are cases of pemphigus vulgaris with epidemiologic, clinical and histopathologic characteristics similar to those of “endemic pemphigus vulgaris” (EPV) in…
Metformin in dermatology: an overview.
For several decades, metformin has been used as an oral hypoglycaemic agent, where it is the first line of treatment in overweight and obese type 2 diabetic patients. This is because it decreases the hepatic glucose output and acts as…
Getagd met bullous pemphigoid, leukocytoclastic vasculitis, lichen planus, psoriasiform drug eruption
Geplaatst in Around the Globe, News and Information
Geplaatst in Around the Globe, News and Information
