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Targeting DSG3: from pemphigus to squamous cell carcinoma

Desmosomes are specialized structures of the cell membrane that are crucial for the establishment and maintenance of cell-cell adhesion and tissue integrity. Transmembrane proteins of desmosomes, desmogleins, and desmocollins are responsible for extracellular binding and, thus, are important for interkeratinocyte

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Geplaatst in News and Information

Cicatricial pemphigoid

What is cicatricial pemphigoid? Cicatricial pemphigoid is an autoimmune disease that is characterised by blistering lesions on mucous membranes. It is also called benign mucous membrane pemphigoid or oral pemphigoid. Areas commonly involved are the oral mucosa (lining of the mouth) and conjunctiva

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Geplaatst in Around the Globe

Skin Disease, Autoimmune (Pemphigus) in Dogs


Pemphigus in Dogs Pemphigus is the general designation for a group of autoimmune skin diseases involving ulceration and crusting of the skin, as well as the formation of fluid-filled sacs and cysts (vesicles), and pus filled lesions (pustules). Some types

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Geplaatst in Around the Globe, News and Information
The P/P Registry has been approved by the Western Institutional Review Board (WIRB) and is actively enrolling participants.