We read with interest the study by Koga H et al and we believe that in light of recent observations including our data the “desmoglein compensation theory” as a explanation for localization of blisters should be revisited. Although the disruption…
Miesięczne archiwum: October 2012
Is there an emergent need to modify the Desmoglein compensation theory in pemphigus on the basis of ELISA data and alternative pathogenic mechanisms ?
Tagi: autoantibodies, desmoglein, pemphigus, theory
Napisano w Around the Globe, News and Information
Napisano w Around the Globe, News and Information
Etiology of pyrexia in pemphigus patients: A dermatologist’s enigma
Pęcherzyca vulgaris (PV) is a rare immunobullous dermatosis with worldwide distribution. The core manifestation of the condition is mucosal erosions and easily ruptured bullae that emerge on an apparently normal skin and mucous membranes or on an erythematous base. It…
Napisano w Around the Globe, News and Information
Retrospective analysis of 12 Korean patients with paraneoplastic pemphigus
Paraneoplastic pemphigus (PNP) is a rare, life-threatening, autoimmune, mucocutaneous blistering disease associated with neoplasia. Both humoral and cellular immunity are involved in the pathogenesis of PNP. Characteristically, PNP has a diverse spectrum of clinical and immunopathological features. We retrospectively analyzed…
Tagi: diagnostic criteria, diversity, paraneoplastic pemphigus
Napisano w Around the Globe, News and Information
Napisano w Around the Globe, News and Information
Myasthenia gravis, castleman disease, pemphigus, and anti-phospholipid syndrome
Introduction: Myasthenia gravisis an autoimmune disease marked by neuromuscular transmission failure at the neuromuscular junction. Castleman disease is a rare lymphoproliferative disease characterized by non-cancerous angiofolicular hyperplasia of lymphatic tissue. Methods and results: We describe a young man with rapid,…
