Purpose To evaluate the therapeutic effects of topical tacrolimus ointment on refractory inflammatory ocular surface diseases. Design Retrospective interventional consecutive case series. Methods In Severance Hospital, Seoul, South Korea, 0.02% tacrolimus ointment was topically applied 1 to 3 times per…
Arquivos do Blog
Application for Tacrolimus Ointment in Treating Refractory Inflammatory Ocular Surface Diseases
Marcados com: refractory inflammatory ocular surface diseases, steroid, Tacrolimus Ointment
Publicado em Around the Globe, News and Information
Publicado em Around the Globe, News and Information
An attempt to develop mouse model for anti-laminin γ1 pemphigoid.
BACKGROUND: We recently reported that the autoantibodies of anti-p200 pemphigoid sera react with laminin γ1 and renamed this entity as anti-laminin γ1 pemphigoid. However, it has not been clarified whether the anti-laminin γ1 autoantibodies, particularly those to the C-terminal integrin binding…
Marcados com: anti-laminin, bunny, mice, mouse, rabbit
Publicado em Around the Globe, News and Information
Publicado em Around the Globe, News and Information
Carbon Dioxide Laser Treatment in Hailey-Hailey Disease: A Series of 8 Patients.
OBJECTIVES: Hailey-Hailey disease (HHD), or benign familial pemphigus, is a rare autosomal dominant genodermatosis characterized by the formation of blisters. Eruptions are usually located in large skin folds, and when blisters become infected the condition can be very painful and disabling.…
Marcados com: carbon dioxide, Hailey-Hailey disease, laser
Publicado em Around the Globe, Treatment and Medication
Publicado em Around the Globe, Treatment and Medication
Lobar torsion after lung transplantation
Lobar torsion is a rare complication after lung transplantation. Here we report a case of right middle lobe (RML) torsion after bilateral sequential lung transplantation (BLTx). This 30-year-old lady underwent BLTx for bronchiolitis obliterans due to paraneoplastic pemphigus. The right…
Marcados com: extracorporeal membrane oxygenation, lung transplantation, pemphigus, torsion abnormality
Publicado em Around the Globe, News and Information
Publicado em Around the Globe, News and Information
Endemic pemphigus in the peruvian Amazon: epidemiology and risk factors for the development of complications during treatment
BACKGROUND: Pemphigus is an autoimmune blistering disease. According to a report, in areas of endemic pemphigus foliaceus (EPF) in Peru there are cases of pemphigus vulgaris with epidemiologic, clinical and histopathologic characteristics similar to those of “endemic pemphigus vulgaris” (EPV) in…
Metformin in dermatology: an overview.
For several decades, metformin has been used as an oral hypoglycaemic agent, where it is the first line of treatment in overweight and obese type 2 diabetic patients. This is because it decreases the hepatic glucose output and acts as…
Marcados com: bullous pemphigoid, leukocytoclastic vasculitis, lichen planus, psoriasiform drug eruption
Publicado em Around the Globe, News and Information
Publicado em Around the Globe, News and Information
Pemphigus foliaceus masquerading as IgA pemphigus and responding to dapsone
A 14-year-old male presented with seven years history of recurrent episodes of fluid filled, itchy and eroded lesions over the body not responding to oral corticosteroids and azathioprine. Dermatological examination revealed crusted plaques and erosions in a seborrheic distribution. Histopathology…
Marcados com: Dapsone, IgA, IgA pemphigus, pemphigus, pemphigus foliaceus
Publicado em Around the Globe, News and Information
Publicado em Around the Globe, News and Information
Acantholysis revisited: Back to basics
Acantholysis means loss of coherence between epidermal cells due to the breakdown of intercellular bridges. It is an important pathogenetic mechanism underlying various bullous disorders, particularly the pemphigus group, as well as many non-blistering disorders. Although a well-known concept, the…
Marcados com: acantholysis, Nikolsky′s sign, primary, secondary
Publicado em Around the Globe, News and Information
Publicado em Around the Globe, News and Information
Clinical Relevance of Autoantibodies in Patients with Autoimmune Bullous Dermatosis
The authors present their experience related to the diagnosis, treatment, and followup of 431 patients with bullous pemphigoid, 14 patients with juvenile bullous pemphigoid, and 273 patients with pemphigus. The detection of autoantibodies plays an outstanding role in the diagnosis…
Marcados com: autoantibodies, autoimmune, bullous dermatosis, bullous pemphigoid, IgA pemphigoid, pemphigoid, pemphigus, pemphigus vulgaris
Publicado em Around the Globe, News and Information
Publicado em Around the Globe, News and Information
Paraneoplastic Pemphigus: A Paraneoplastic Autoimmune Multiorgan Syndrome or Autoimmune Multiorganopathy?
Paraneoplastic pemphigus (PNP), a clinically and immunopathologically distinct mucocutaneous blistering dermatosis, is a severe form of autoimmune multiorgan syndrome generally associated with poor therapeutic outcome and high mortality. This IgG-mediated disease is initiated by an obvious or occult lymphoproliferative disorder…
Marcados com: autoimmune, paraneoplastic pemphigus, pemphigus, PNP
Publicado em Around the Globe, News and Information
Publicado em Around the Globe, News and Information
