Pemphigus vulgaris treated with adalimumab: case study

ABSTRACT The study describes the case of a patient with a clinical and histopathological diagnosis of pemphigus vulgaris accompanied by severe side‐effects of combined immunosuppressive therapy, who achieved a remission of the disease with adalimumab. Pemphigus vulgaris is a chronic blistering disease of the skin and mucous membranes. Before corticosteroids were introduced, mortality was high. Corticosteroids are currently used as first‐line therapy. To reduce the dose of corticosteroids, therapeutic combinations with

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corticosteroid‐sparing immunosuppressive agents are used. The therapy brings a number of complications due to its side effects. To achieve a remission of the disease by treating our patient with combined immunosuppressives, we administered adalimumab and achieved a very

from MedWorm: Pemphigus

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