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Regulatory T Cells Are Severely Reduced in PV

This new study, published in the journal "Dermatology", shows that a severe reduction of T (Treg) cells may be involved in the pathogenesis of pemphigus vulgaris (PV), an autoimmune blistering disease.

Опубликовано в Medical

Keratoprosthesis steadily gaining ground on corneal grafting, surgeons say

PHILADELPHIA — Permanent keratoprosthesis is becoming a viable and popular alternative to corneal transplantation, according to two specialists speaking here at the 2007 Wills Eye Hospital Annual Alumni Conference.

Опубликовано в Medical

Anti-TNF Therapy for Mucous Membrane Pemphigoid

Mucous Membrane Pemphigoid, also known as Cicatricial Pemphigoid, is a serious autoimmune blistering disorder that can result in blindness and other complications as the result of scarring of the mucous membranes.  To our knowledge, there have been 2 reported uses

Опубликовано в Medical

Rituximab: A New Treatment for Recalcitrant PV?

Rituximab (RTX) is anti-CD20 chimeric antibody that selectively targets B cells.  CD20 is a molecule that functions as an antigen for it.  CD20 is expressed on mature antibody producing B cells, but not on plasma cells.(1) The FDA has approved

Опубликовано в Medical

Treating Pemphigus and Pemphigoid with IVIg

By Michelle Greer, RN, MBAandMichael T. Rigas, PharmDCrescent Healthcare, Inc. “The information provided in this article has been edited by Drs. Jean-Claude Bystryn and Sergei Grando of the IPPF Medical Advisory Baord. There are several companies that provided IVIG at

Опубликовано в Medical

Is Pemphigus More Common in Women?

The International Pemphigus & Pemphigoid Foundation and Dr. Sarah Brenner recently conducted a survey on some aspects of pemphigus, in particular the gender distribution of the patients, and the relationship between the disease and the use of sex hormones.

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Опубликовано в Medical

Herbal Medication can have adverse side effects

Herbal supplements are used widely, and some of these supplements may stimulate the immune system in ways that could be harmful for people who have or are prone to autoimmune diseases.  There are a number of herbal medications that have

Опубликовано в Medical


The function of the immune system was critical to survival of our species. Prior to the 20th century man’s greatest killers were, in fact, infectious diseases. It is important to note that not everyone’s immune system functions in the same

Опубликовано в Medical

What you need to know about RituxiMab

Rituximab is a laboratory manufactured antibody that targets the cells in our bodies that produce antibodies. This was genetically engineered and is the first monoclonal antibody to be approved by the FDA for the treatment of cancer. The current indication

Опубликовано в Medical

Pemphigus: An Acronym for a Disease with Multiple Causes

by Sarah Brenner, MD, Jacob Mashiah, MD, Einat Tamir, MD, Ilan Goldberg, MD and Yonit Wohl, MD, Department of Dermatology, Tel Aviv Sourasky Medical Center, and Sackler Faculty of Medicine, Tel Aviv University, Israel Pemphigus is generally considered to stem

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Опубликовано в Medical
The P/P Registry has been approved by the Western Institutional Review Board (WIRB) and is actively enrolling participants.