Effektivität und Sicherheit von Rituximab beim Pemphigus: Ergebnisse aus dem Deutschen Register für Autoimmunerkrankungen

Опубликовано June 15, 2013 Автор: Cristo Rey Intern

Klinik für Dermatologie, Allergologie und Venerologie, Universität Lübeck, Deutschland Klinik für Dermatologie und Allergologie, Philipps-Universität Marburg, Deutschland Klinik und Poliklinik für Dermatologie und Venerologie, Universität Köln, Deutschland Klinik für Dermatologie, Technische Universität Dresden, Deutschland Abteilung Rheumatologie, LMU München, Deutschland Abteilung…

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Метки: autoantibody, bullous disease, childhood pemphigus vulgaris, pemphigus vulgaris
Опубликовано в Around the Globe, News and Information, Treatment and Medication

Pemphigus Subaigu Malin à Bulles Extensives

Опубликовано June 11, 2013 Автор: Cristo Rey Intern

Variété de pemphigus vulgaire se caractérisant par la présence de bulles qui finissent par confluer (se rejoindre) et se rompre, créant ainsi de vastes surfaces laissant la peau à vif qui suinte et qui devient très douloureuse. Généralités Le pemphigus…

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Метки: pemphigus vulgaris
Опубликовано в Around the Globe, News and Information

Pemphigus Vulgaris Activity Score and Assessment of Convergent Validity.

Опубликовано June 7, 2013 Автор: Cristo Rey Intern

Pemphigus is a rare autoimmune blistering disease with different phenotypes. The evaluation of therapeutic interventions requires a reliable, valid and feasible to use measurement. However, there is no gold standard to measure the disease activity in clinical trials. In this…

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Метки: pemphigus, pemphigus vulgaris, phenotypes, PVAS
Опубликовано в Around the Globe

Oral Inflammation in Small Animals

Опубликовано June 3, 2013 Автор: Cristo Rey Intern

The oral cavity can be affected by a wide variety of disorders characterized by inflammation of the gingiva and/or oral mucosa. In dogs and cats, differential diagnoses for generalized oral inflammatory disorders include plaque-reactive mucositis, chronic gingivostomatitis, eosinophilic granuloma complex,…

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Метки: Canine, cat, chronic gingivostomatitis, dog, eosinophilic granuloma complex, erythema multiforme, feline, pemphigoid, pemphigus
Опубликовано в Around the Globe, News and Information

Bullous pemphigoid and internal diseases – A case-control study.

Опубликовано May 26, 2013 Автор: Cristo Rey Intern

To study associations of bullous pemphigoid (BP) with internal diseases, we conducted a retrospective case control study assessing the frequency of selected diseases – diabetes mellitus, neurological diseases, malignant tumors, benign prostate hyperplasia, hypertension and ischemic heart disease in patients…

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Метки: bullous pemphigoid, cancer, diabetes mellitus, etiopathogenesis, neurological disorder
Опубликовано в Around the Globe, News and Information

“Coaches Corner” – New Coaches, New Perspectives

Опубликовано May 22, 2013 Автор: marc

Although everyday (whether I like it or not), I am reminded what it is like to live with Pemphigus and Pemphigoid, I am fortunate because I have the opportunity to share my story and build relationships. Recently, the IPPF has…

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Метки: coach, help, support
Опубликовано в The Coaches Corners

Targeted Delivery of Tumor Necrosis Factor-Related Apoptosis-Inducing Ligand To Keratinocytes with A Pemphigus Monoclonal Antibody

Опубликовано May 22, 2013 Автор: Cristo Rey Intern

We determined the feasibility of using an anti-desmoglein (Dsg) monoclonal antibody, Px44, to deliver a biologically active protein to keratinocytes. Recombinantly produced Px44-green fluorescent protein (GFP) injected into mice and skin organ culture delivered GFP to the cell surface of…

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Метки: desmoglein, Dsg, GFP, Green fluorescent protein, HA, head and neck squamous cell carcinoma, hemaggultinin, HNSCC, scFvs, single chain variable fragment antibodies, TRAIL, tumor, tumor necrosis factor -related apoptosis-inducing ligand
Опубликовано в Around the Globe, News and Information

The frequency of osteoporosis in patients with pemphigus vulgaris on treatment

Опубликовано May 14, 2013 Автор: Cristo Rey Intern

Background: Pemphigus vulgaris was almost fatal before the advent of glucocorticoids. Unfortunately, the high doses and prolonged administration of glucocorticoids, which often needed to control the disease, result in numerous adverse effects many of which are serious. Aims: To evaluate the patients…

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Метки: glucocorticoids, osteoporosis, pemphigus
Опубликовано в Around the Globe, News and Information

Resistant oral mucosal lesions in pemphigus vulgaris responsive to double filtration plasmapheresis: First case report from Turkey.

Опубликовано May 10, 2013 Автор: Cristo Rey Intern

Background Adjuvant therapeutic methods are employed when pemphigus vulgaris (PV) fails to be controlled by conventional corticosteroid treatment. Objective: The efficacy of double filtration plasmapheresis (DFPP) was investigated in a PV patient with severe, refractory mucosal disease. Methods A total…

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Метки: Double filtration plasmapheresis, pemphigus vulgaris
Опубликовано в Around the Globe, News and Information

Prevalence and Clinical Significance of Anti-Laminin 332 Autoantibodies Detected by a Novel Enzyme-Linked Immunosorbent Assay in Mucous Membrane Pemphigoid

Опубликовано May 8, 2013 Автор: Cristo Rey Intern

IMPORTANCE A rare variant of mucous membrane pemphigoid (MMP) is characterized by circulating anti-laminin 332 (Lam332) autoantibodies and seems to be associated with concurrent malignant neoplasms. OBJECTIVE To determine the prevalence and clinical significance of anti-Lam332 autoantibody detection from a large…

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Метки: Anti-Laminin 332, autoantibodies, Autoimmune bullous diseases
Опубликовано в Around the Globe, News and Information