By Professor Martin M Black, MD Pemphigus and its variants are rare autoimmune disorders characterized by loss of cell to cell cohesion between keratinocytes leading to intra-epidermal blistering. In all types of pemphigus, antibodies are directed against antigens in the…
Blog Archives
Pemphigus Ethnicity & ELISA Studies
Tagged with: autoantibodies, dermatology, immunodermatopathological, immunofluorescent, intercellular, keratinocytes, transmembrane
Posted in Medical
Posted in Medical
Cicatricial Pemphigoid Has Numerous Manifestations
by Dr. Joyce Rico Cicatricial pemphigoid is an autoimmune blistering disease that predominately effects mucous membranes, including the mouth and throat, eyes, and genitalia. Patients with skin involvement present with tense blisters or erosion, often on the head and neck,…
Tagged with: antiinflammatory, autoantibodies, cyclophosphamide, dermatology, gynecologists, intralesional, manifestation, ophthalmologists, otolaryngologists
Posted in Medical
Posted in Medical
Why Lesions Occur at Different Sites
By Grant J. Anhalt, M.D. Johns Hopkins Dermatology I will attempt to clarify what we know about the antibody response in various forms of pemphigus and how the distribution of the targeted antigens affects the location of lesions. The synthesis…
Tagged with: acantholysis, autoantibodies, autoantibody, autoimmunity, dermatology, keratinocyte, manipulation, mucocutaneous, paraneoplastic
Posted in Medical
Posted in Medical
Tests for Pemphigus
by Ernest H. Beutner, Ph.D.*Professor of Microbiology and Dermatology, University of Buffalo; School of Medicine and Biomedical Sciences; Buffalo, NY Patients with pemphigus may benefit by working with their doctors to gain a better understanding of the tests used to…
Tagged with: certificates, dermatology, erythematosus, evaluations, herpetiformis, laboratories, paraneoplastic
Posted in Medical
Posted in Medical
International Survey Results
This is not a scientific study, but we can draw some conclusions that would tend to support the current statistics especially for PV. The one big difference would be the correlation between males and females. We had females returning surveys…
