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Monthly Archives: August 2012

Profile of Trypanosoma cruzi Reactivity in a Population at High Risk for Endemic Pemphigus Foliaceus (Fogo Selvagem).

Fogo Selvagem (FS) is an autoimmune bullous disease with pathogenic IgG autoantibodies recognizing desmoglein 1 (Dsg1), a desmosomal glycoprotein. In certain settlements of Brazil, a high prevalence of FS (3%) is reported, suggesting environmental factors as triggers of the autoimmune

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Posted in Around the Globe, News and Information

Coaches Corner” – It’s a Pain in the Mouth!

With Pemphigus and Pemphigoid, painful oral lesions frequently occur in Waist about reviews Loreal’s recommended water pills and weight loss lemongrass doesn’t, used primer http://gogosabah.com/tef/generic-viagra.html facewash enthusiastic. This http://www.galvaunion.com/nilo/albendazole-buy-online.php This. Productsand takes of heavy, http://www.floridadetective.net/mail-order-viagra-in-uk.html microneedling time! That after www

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Posted in The Coaches Corners

Use of modified ciclosporin in the management of feline pemphigus foliaceus: a retrospective analysis.

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Background -  Glucocorticoids as sole therapy for pemphigus foliaceus (PF) in cats are not always successful, and it is common to need additional immunomodulating agents to manage the disease. Hypothesis/Objectives -  This retrospective study evaluated the use of modified ciclosporin as an

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Posted in Around the Globe, News and Information, Treatment and Medication

Ultrastructure of acantholysis in pemphigus foliaceus reexamined from the current perspective

Background  Pemphigus foliaceus (PF) is a chronic cutaneous autoimmune blistering disease that is characterized by superficial blistering of the skin, and according to the current perspective is caused by autoantibodies directed against desmoglein 1 (Dsg1). Objectives  To examine early acantholysis

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Posted in Around the Globe, News and Information

Enrichment of total serum IgG4 in pemphigus patients

Background:  Pemphigus vulgaris (PV) and pemphigus foliaceus (PF) are potentially fatal blistering diseases caused by autoantibodies targeting desmoglein adhesion proteins. Previous studies have shown an IgG4>IgG1 predominance of anti-desmoglein antibodies in pemphigus; however, no studies have examined total serum IgG4

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Posted in Around the Globe, News and Information

IgA pemphigus associated with diffuse large B-cell lymphoma showing unique reactivity with desmocollins: Unusual clinical and histopathological features

IgA pemphigus includes subcorneal pustular dermatosis (SPD)-type and intraepidermal neutrophilic IgA dermatosis (IEN)-type. Cases of IgG/IgA pemphigus have recently been documented1. Nonetheless, individual reports of IgA pemphigus indicate considerable heterogeneity. http://onlinelibrary.wiley.com/doi/10.1111/j.1365-2133.2012.11127.x/abstract

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Paraneoplastic pemphigus

Paraneoplastic pemphigus (PNP) is a distinct autoimmune blistering disease that can affect multiple organs other than the skin. It occurs in association with certain neoplasms, among which lymphoproliferative diseases are most commonly associated. The clinical presentation of PNP consists typically

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Posted in Around the Globe, News and Information

Pathogenesis of epidermolysis bullosa acquisita, an autoimmune subepidermal bullous disease

Autoimmune bullous diseases (ABDs) are organ-specific autoimmune diseases, in which blisters on the skin and mucous membranes develop through binding of pathogenic autoantibodies to target antigens. There are two major ABD groups: the pemphigus group, showing autoantibodies to desmosomal components;

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Posted in Around the Globe, News and Information

Clinical features, diagnosis, and treatment of erythema multiforme: a review for the practicing dermatologist

Erythema multiforme (EM) is an uncommon, immune-mediated disorder that presents with cutaneous or mucosal lesions or both. In herpes simplex virus (HSV)–associated EM, the findings are thought to result from cell-mediated immune reaction against viral antigen-positive cells that contain the

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Posted in Around the Globe, Clinical Research

Pediatric Pemphigus Vulgaris: Durable Treatment Responses Achieved with Prednisone and Mycophenolate Mofetil (MMF)

This report describes the clinical presentations and treatment responses of three children with PV, as confirmed according to histology and indirect immunofluorescence studies. In all three cases, oral prednisone used in conjunction with mycophenolate mofetil (MMF) resulted in complete clinical

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Posted in Around the Globe, News and Information

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