We read with interest the study by Koga H et al and we believe that in light of recent observations including our data the “desmoglein compensation theory” as a explanation for localization of blisters should be revisited. Although the disruption…
Monthly Archives: October 2012
Is there an emergent need to modify the Desmoglein compensation theory in pemphigus on the basis of ELISA data and alternative pathogenic mechanisms ?
Tagged with: autoantibodies, desmoglein, pemphigus, theory
Posted in Around the Globe, News and Information
Posted in Around the Globe, News and Information
Etiology of pyrexia in pemphigus patients: A dermatologist’s enigma
Pemphigus vulgaris (PV) is a rare immunobullous dermatosis with worldwide distribution. The core manifestation of the condition is mucosal erosions and easily ruptured bullae that emerge on an apparently normal skin and mucous membranes or on an erythematous base. It…
Retrospective analysis of 12 Korean patients with paraneoplastic pemphigus
Paraneoplastic pemphigus (PNP) is a rare, life-threatening, autoimmune, mucocutaneous blistering disease associated with neoplasia. Both humoral and cellular immunity are involved in the pathogenesis of PNP. Characteristically, PNP has a diverse spectrum of clinical and immunopathological features. We retrospectively analyzed…
Tagged with: diagnostic criteria, diversity, paraneoplastic pemphigus
Posted in Around the Globe, News and Information
Posted in Around the Globe, News and Information
Myasthenia gravis, castleman disease, pemphigus, and anti-phospholipid syndrome
Introduction: Myasthenia gravisis an autoimmune disease marked by neuromuscular transmission failure at the neuromuscular junction. Castleman disease is a rare lymphoproliferative disease characterized by non-cancerous angiofolicular hyperplasia of lymphatic tissue. Methods and results: We describe a young man with rapid,…
Tagged with: antiphospholipid syndrome, Castleman disease, interleukin-6, myasthenia gravis, pemphigus vulgaris
Posted in Around the Globe, News and Information
Posted in Around the Globe, News and Information
