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A case of stable oral pemphigus vulgaris on low dose immunosuppressive therapy

The clinical and epidemiological features of pemphigus vulgaris (PV) are well documented but there remain few reports of oesophageal involvement of PV. Although previously considered to be rare, recent reports have suggested that up to 87% of patients with PV

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Pemphigus foliaceus masquerading as IgA pemphigus and responding to dapsone

A 14-year-old male presented with seven years history of recurrent episodes of fluid filled, itchy and eroded lesions over the body not responding to oral corticosteroids and azathioprine. Dermatological examination revealed crusted plaques and erosions in a seborrheic distribution. Histopathology

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Randomized double blind trial of prednisolone and azathioprine

Background  The classic treatment for pemphigus vulgaris is prednisolone. Immunosuppressive drugs can be used in association. Objective  To compare the efficacy of Azathioprine in reducing the Disease Activity Index (DAI). Patients and methods  A double blind randomized controlled study was conducted on 56

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Multiple cutaneous neutropenic ulcers associated with azathioprine

We report a case of neutropenic ulceration in a 42-year-old woman receiving azathioprine for pemphigus vulgaris. She developed multiple indolent ulcers involving the nose, neck, and back, after about 6-8 weeks following commencement of azathioprine 50 mg daily. The ulcers

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Azathioprine in the treatment of Autoimmune Blistering diseases

Although there are no standard guidelines for the treatment of autoimmune blistering diseases, azathioprine has shown good efficacy in acquired autoimmune blistering diseases, and is well tolerated. Side effects of azathioprine normally occur in mild variants. Severe reactions are due

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A Systematic Review of Treatments for Bullous Pemphigoid

By Nonhlanhla Khumalo, Dedee Murrell, Fenella Wojnarowska & Gudula Kirtschig Archives of Dermatology March 2002 Vol 138 pages 385-389. www.archdermatol.com This review is different from the usual type of review you might read about bullous diseases in that by being

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Pemphigus in China

By Dr. Pan Meng Pemphigus is a group of organ-specific autoimmune disorders, including pemphigus vulgaris (PV), pemphigus foliaceus (PF) and paraneoplastic pemphigus (PNP). PV is the most common disease and represents this kind of potentially life-threatening disease. It is characterized

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Remissions in Pemphigus

By Jean-Claude Bystryn, M.D. Professor of Dermatology Director of Immunofluorescence Laboratory The Ronald O. Perelman Department of Dermatology New York University Medical Center Pemphigus vulgaris (PV) can enter into remissions in which all manifestations of the disease disappear and all

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