Pemphigus foliaceus (PF) is the most common autoimmune skin disease of dogs and other animal species. Although PF can spontaneously affect dogs of any breed, it appears more prevalent in Akita Inus and chow chows in the United States. The…
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Pemphigus foliaceus masquerading as IgA pemphigus and responding to dapsone
A 14-year-old male presented with seven years history of recurrent episodes of fluid filled, itchy and eroded lesions over the body not responding to oral corticosteroids and azathioprine. Dermatological examination revealed crusted plaques and erosions in a seborrheic distribution. Histopathology…
Tagged with: Dapsone, IgA, IgA pemphigus, pemphigus, pemphigus foliaceus
Posted in Around the Globe, News and Information
Posted in Around the Globe, News and Information
Equine Pemphigus Foliaceus
Pemphigus foliaceus (pem-fi-gus foli-a-shus) is an auto immune disease that affects humans and dogs and, to a lesser extent, cats and horses. In horses, it is characterized by primary lesions that often begin on the head and lower extremities; secondary…
Tagged with: equine, horse, pemphigus, pemphigus foliaceus
Posted in Around the Globe, News and Information
Posted in Around the Globe, News and Information
Feline Pemphigus Foliaceus
Pemphigus foliaceus (PF) is an immune-mediated disease that causes pustules and crusted lesions, most commonly on the pinnae, nasal planum, periocular area, chin, feet of affected cats. Acantholytic cells caused by dehydration of intercellular adhesions are often seen on cytology…
Tagged with: cat, feline, pemphigus, pemphigus foliaceus
Posted in Around the Globe, News and Information
Posted in Around the Globe, News and Information
Immunohistochemistry for immunoglobulin g4 on paraffin sections for the diagnosis of pemphigus.
Context.-Pemphigus is a group of autoimmune vesiculobullous diseases characterized by immunoglobulin G (IgG) antibodies directed against desmosomal adhesion proteins, with IgG4 being the predominant subclass in active diseases. Direct immunofluorescence for IgG performed on fresh-frozen tissue plays a crucial role…
Tagged with: immunofluorescence, immunoglobulin G, pemphigus, pemphigus foliaceus, vesiculobullous disease
Posted in Around the Globe, News and Information
Posted in Around the Globe, News and Information
Pemphigus foliaceus masquerading as IgA pemphigus and responding to dapsone
A 14-year-old male presented with seven years history of recurrent episodes of fluid filled, itchy and eroded lesions over the body not responding to oral corticosteroids and azathioprine. Dermatological examination revealed crusted plaques and erosions in a seborrheic distribution. Histopathology…
Tagged with: azathioprine, desmologlein, dexamethason, immunofluorescent, pemphigus foliaceus
Posted in Around the Globe, News and Information
Posted in Around the Globe, News and Information
Polymorphisms of HLA microsatellite marker in Tunisian pemphigus foliaceus.
Pemphigus foliaceus (PF) is an autoimmune blistering skin disease that partly results from genetic factors, especially from human leucocyte antigen (HLA) class II genes. Several data have reported the involvement of microsatellite (STR) markers across different regions of the HLA…
Tagged with: autoimmune blistering skin disease, genetic, pemphigus foliaceus, polymorphisms
Posted in Around the Globe, News and Information
Posted in Around the Globe, News and Information
Clinical and immunological profile of umbilical involvement in pemphigus vulgaris and pemphigus foliaceus
Background. Pemphigus vulgaris (PV) and pemphigus foliaceus (PF) are autoimmune vesicobullous disorders with IgG autoantibodies directed against desmoglein (Dsg)1 and 3, which lead to intraepidermal acantholysis. Aim. To characterize the clinical and immunological profile of patients with PF or PV with umbilical…
Tagged with: desmoglein, Erythema, pemphigus foliaceus, pemphigus vulgaris
Posted in Around the Globe, Clinical Trials, News and Information
Posted in Around the Globe, Clinical Trials, News and Information
Rituximab in pemphigus
Pemphigus is a chronic, muco-cutaneous autoimmune blistering disorder; two main variants being pemphigus vulgaris (PV) and pemphigus foliaceus (PF). PV is the most common subtype, varying between 75 to 92% of total pemphigus patients. Although no community based studies are undertaken…
Tagged with: corticosteroid, DCP, IgG1, immunosuppressant, MabThera, pemphigus, pemphigus foliaceus, pemphigus vulgaris, rituxmab
Posted in Around the Globe, News and Information
Posted in Around the Globe, News and Information
Ultrastructure of acantholysis in pemphigus foliaceus re-examined from the current perspective
Background Pemphigus foliaceus (PF) is a chronic cutaneous autoimmune blistering disease that is characterized by superficial blistering of the skin, and according to the current perspective is caused by autoantibodies directed against desmoglein (Dsg) 1. Objectives To examine early acantholysis…
Tagged with: desmosomes, hypoplastic, lesions, Nikolsky, pemphigus foliaceus
Posted in Around the Globe, News and Information
Posted in Around the Globe, News and Information
