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Pemphigus: An Acronym for a Disease with Multiple Causes

by Sarah Brenner, MD, Jacob Mashiah, MD, Einat Tamir, MD, Ilan Goldberg, MD and Yonit Wohl, MD, Department of Dermatology, Tel Aviv Sourasky Medical Center, and Sackler Faculty of Medicine, Tel Aviv University, Israel Pemphigus is generally considered to stem

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文章分类 Medical

Pemphigus & Ocular Involvement: A Survey

by Edward Tenner, M.D. INTRODUCTION The autoimmune bullous skin diseases, pemphigus (with major subsets pemphigus vulgaris, pemphigus foliaceus and paraneoplastic pemphigus) and the more common bullous pemphigoid (with variant disease phenotypes of cicatricial pemphigoid and gestational pemphigoid) each may have

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文章分类 Medical

Pemphigus: A Historical Perspective

By Robert Jordon, M.D.Professor and Chairman, Department of Dermatology,University of TexasHouston, Texas Historical Perspective The term pemphigus was most likely in use in the ancient world, but the first recorded instance was by Hippocrates (460-370 BC) who described pemphigoid fever

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文章分类 Medical

Pemphigus Ethnicity & ELISA Studies

By Professor Martin M Black, MD Pemphigus and its variants are rare autoimmune disorders characterized by loss of cell to cell cohesion between keratinocytes leading to intra-epidermal blistering. In all types of pemphigus, antibodies are directed against antigens in the

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文章分类 Medical

Companion Animals, Too, Can Get Pemphigus

by Thierry Olivry, DrVet, PhD, DipACVD, DipECVD, Associate Professor of Dermatology, Department of Clinical Sciences, College of Veterinary Medicine, NC State University, Raleigh, North Carolina, and Adjunct Clinical Associate Professor of Dermatology, Department of Dermatology, School of Medicine, University of

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文章分类 Medical

Why Lesions Occur at Different Sites

By Grant J. Anhalt, M.D. Johns Hopkins Dermatology I will attempt to clarify what we know about the antibody response in various forms of pemphigus and how the distribution of the targeted antigens affects the location of lesions. The synthesis

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文章分类 Medical

Development of Non-hormonal Treatment of Pemphigus

By Sergei A. Grando, MD, PhD, DSci Professor of Dermatology University of California Davis The Need for Alternative Therapies for Pemphigus. In autoimmune pemphigus, systemic glucocorticosteroid treatment is life saving but may cause severe side effects. Pemphigus patients therefore need

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文章分类 Medical

Exploring the “Wildfire” World of Pemphigus Foliaceous

by Luis A. Diaz, M.D. Professor and Chairman Department of Dermatology Medical College of Wisconsin Milwaukee, Wisconsin Pemphigus foliaceous (PF) one of the major clinical variants of pemphigus, is characterized by superficial blisters and anti-epidermal autoantibodies. The epidermal antigen with

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文章分类 Medical

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